| 100% | SOPHIABUSH | 10 | The actress who played one of the central characters, Brooke Davis, on "One Tree Hill" |
| 52% | BUSH | 4 | Sophia —, US actress who played Brooke Davis in television drama series One Tree Hill |
| 52% | SUSANSARANDON | 13 | Actress who played Louise, one of the title characters on the run in 1991's "Thelma & Louise": 2 wds. |
| 51% | ISABELSANFORD | 13 | Actress who played Louise Jefferson, the main character on the '70s sitcom "The Jeffersons" which is one of the longest-running sitcoms: 2 wds. |
| 50% | HELENEYORKE | 11 | "The Good Fight" actress who plays one of the siblings on 36-Across (2 wds.) |
| 46% | BROWN | 5 | Millie Bobby ___, actress who played the character of Eleven on "Stranger Things" |
| 44% | SUSIEESSMAN | 11 | Actress who plays the foul-mouthed wife of the main character's manager Jeff on "Curb Your Enthusiasm": 2 wds. |
| 43% | ALLISON | 7 | Janney who plays one of the moms on TV's "Mom" |
| 43% | ASHLEY | 6 | One of the twins who played Michelle on Full House |
| 43% | OTERI | 5 | Actress Cheri who was one of the cheerleaders on "SNL" |
| 43% | DANIELKALUUYA | 13 | Actor who plays Slim, one of the title characters on the run in 2019's "Queen & Slim": 2 wds. |
| 42% | WARREN | 6 | With 35-Across, actor who played Clyde, one of the title characters on the run in 1967's "Bonnie and Clyde" |
| 42% | LIZZYCAPLAN | 11 | "Masters of Sex" actress who plays one of Toby Fleishman's best friends on "Fleishman Is in Trouble" (2 wds.) |
| 41% | TIFFANYHADDISH | 14 | "Keanu" actress who adopted one of the cats that played Keanu in the film: 2 wds. |
| 41% | FELICITYJONES | 13 | "Rogue One" actress who plays Ruth Bader Ginsburg in "On the Basis of Sex" (2 wds.) |
| 41% | RETTA | 5 | One-named actress who plays Ruby Hill on "Good Girls" |
| 41% | BOB | 3 | Actor McGrath who was one of the original human characters on "Sesame Street" |
| 41% | LILYCOLLINS | 11 | Actress who plays the title character on 46-Across (2 wds.) |
| 41% | LINDALAVIN | 10 | Actress who played the title character on the sitcom "Alice": 2 wds. |
| 40% | EDIE | 4 | First name of the actress who played Carmela on "The Sopranos" |
| 40% | CAMILLERAZAT | 12 | Actress who plays the title character's new friend on 46-Across (2 wds.) |
| 40% | KRISTEN | 7 | Actress Bell of "Forgetting Sarah Marshall," who plays Eleanor, the lead character in 15a |
| 40% | JESSSALGUEIRO | 13 | Actress who plays Freddy's roommate on the Paramount+ reboot of "Frasier" (2 wds.) |
| 40% | EDIEFALCO | 9 | "The Sopranos" actress who played the title character on "Nurse Jackie": 2 wds. |
| 40% | GINA | 4 | First name of the actress who plays Jane on "Jane the Virgin" |
| 40% | EDIE | 4 | First name of the actress who plays Tommy on CBS's "Tommy" |
| 40% | EDIE | 4 | Actress Falco who played the title character on "Nurse Jackie" |
| 40% | CECILYSTRONG | 12 | "Ghostbusters" actress who played the recurring characters Cathy Ann and Kyra on "Saturday Night Live" (2 wds.) |
| 39% | CECILYSTRONG | 12 | "Ghostbusters" actress who plays the recurring characters Cathy Ann and Kyra on "Saturday Night Live" (2 wds.) |
| 39% | ALFONSORIBEIRO | 14 | "Dancing With the Stars" host who played one of Ricky's friends on 19-Across: 2 wds. |