| 100% | REXTILLERSON | 12 | The current US Secretary of State: 2 wds. |
| 81% | STEVENMNUCHIN | 13 | The current US Secretary of the Treasury: 2 wds. |
| 81% | JANETYELLEN | 11 | Current US Secretary of the Treasury: 2 wds. |
| 76% | JAMESMADISON | 12 | US Secretary of State (and fourth president) who oversaw the Louisiana Purchase: 2 wds. |
| 71% | MIGUELCARDONA | 13 | Current US Secretary of Education: 2 wds. |
| 71% | LLOYDAUSTIN | 11 | Current US Secretary of Defense: 2 wds. |
| 67% | REXTILLERSON | 12 | US Secretary of State who was formerly an Exxon executive: 2 wds. |
| 66% | COLINPOWELL | 11 | Former US Secretary of State who's a Vietnam vet: 2 wds. |
| 63% | ALEXANDERHAIG | 13 | US Secretary of State who announced "I am in control here" after President Reagan was shot: 2 wds. |
| 57% | JEFFSESSIONS | 12 | The current US Attorney General: 2 wds. |
| 51% | POWELL | 6 | U.S. secretary of state raised in the Bronx |
| 49% | CYRUSVANCE | 10 | US Secretary of State from 1977-80 |
| 49% | JILLBIDEN | 9 | Current US First Lady who was also the Second Lady from 2009 to 2017: 2 wds. |
| 49% | JOHNBOEHNER | 11 | Republican congressman from Ohio who is the current Speaker of the House: 2 wds. |
| 49% | PETEBUTTIGIEG | 13 | Democratic presidential candidate who's the current mayor of South Bend, Indiana: 2 wds. |
| 49% | DEANRUSK | 8 | U.S. secretary of state tied for the second-longest time in office |
| 48% | PERDUE | 6 | Sonny, current US Secretary of Agriculture |
| 48% | MADELEINE | 9 | Former US Secretary of State Albright |
| 48% | HAIG | 4 | Former US Secretary of State Alexander |
| 48% | PETEBUTTIGIEG | 13 | Current Secretary of Transportation who received a Rhodes Scholarship in 2005: 2 wds. |
| 48% | ALBRIGHT | 8 | Madeleine __; first female US secretary of state |
| 48% | CLINTON | 7 | Hillary —, 2009-13 US Secretary of State |
| 48% | REX | 3 | 2017-2018 US Secretary of State Tillerson |
| 48% | ALBRIGHT | 8 | First female US secretary of state, Madeleine |
| 48% | MICHAELSTRAHAN | 14 | Former NFL defensive end who hosts the current revival of "The $100,000 Pyramid": 2 wds. |
| 47% | FIRETOKENS | 10 | New "currency" on the current season of "Survivor": 2 wds. |
| 47% | HAIG | 4 | Alexander —, US Secretary of State from 1981-82 |
| 47% | VANCE | 5 | Cyrus —, US Secretary of State from 1977-80 |
| 47% | RUSK | 4 | Dean —, US Secretary of State from 1961-69 |
| 47% | KERRY | 5 | John —, US Secretary of State from 2013-17 |