| 100% | REDDRAGON | 9 | The first novel in the Hannibal Lecter saga |
| 50% | DAWN | 4 | "Breaking ___" (final novel in the "Twilight" saga) |
| 47% | MOON | 4 | "The First Men in the ___," 1901 science romance novel by H.G. Wells |
| 45% | THUS | 4 | First word in the translated title of Nietzsche's 1885 novel "Also sprach Zarathustra" |
| 45% | DEADSIMPLE | 10 | 2005 novel by Peter James; first book in the Roy Grace series |
| 45% | WARDROBE | 8 | "The Lion, the Witch and the ___," first novel in the fantasy series "The Chronicles of Narnia" by C.S. Lewis |
| 45% | REDDRAGON | 9 | 1981 novel that introduced the character Hannibal Lecter |
| 44% | TITUSGROAN | 10 | 1946 Mervyn Peake novel; first in the Gormenghast trilogy |
| 43% | JOY | 3 | "___ in the Morning," novel by P.G. Wodehouse first published in 1946 |
| 43% | UNEASY | 6 | P G Wodehouse novel first published in the US in 1916 featuring the character Ira Nutcombe |
| 43% | AGENTLEMANOF | 12 | & 8A 1910 P G Wodehouse novel first published in the US as The Intrusion of Jimmy |
| 43% | CARD | 4 | Credit ___, invention that was first mentioned in the sci-fi novel "Looking Backward" by Edward Bellamy |
| 42% | LUCKOF | 6 | & 6D The —, William Thackeray novel first published in serial form in 1844 |
| 42% | EVE | 3 | The first woman in the Bible |
| 42% | BRITISH | 7 | The first B in the BBC |
| 42% | THESPOILS | 9 | 1897 Henry James novel first published in serial form as The Old Things |
| 42% | MONEY | 5 | "One for the ___" (first novel in the Stephanie Plum series by Janet Evanovich) |
| 42% | INHERITANCE | 11 | First novel in 39-Across's "The Lost Bride" romance series |
| 41% | INTHEWOODS | 10 | 2007 novel that's the first volume in 43-Across's Dublin Murder Squad mystery series (3 wds.) |
| 41% | INTHEWOODS | 10 | 2007 novel that's the first volume in 43-Across's "Dublin Murder Squad" mystery series (3 wds.) |
| 41% | HYDROGEN | 8 | The first element in the periodic table |
| 41% | EMILYBRONTE | 11 | Author of novel Wuthering Heights, first published in 1847 under the pseudonym Ellis Bell |
| 41% | AIS | 3 | & 13D 1982 novel by Sue Grafton; first in the Kinsey Millhone alphabet mystery series |
| 41% | ATOM | 4 | ___ bomb, nuclear weapon which was first mentioned in the sci-fi novel "The World Set Free" by HG Wells |
| 41% | DAWN | 4 | "Breaking ___," fourth novel in "The Twilight Saga" series |