| 100% | ORGAN | 5 | The heart and liver are both examples of this |
| 49% | AGENCIES | 8 | HMRC and the CIA are examples of these |
| 47% | ECLIPSE | 7 | This was Total and of the Heart, for Bonnie Tyler |
| 47% | LANNISTER | 9 | Jaime and Cersei are both members of this House |
| 46% | SOLAR | 5 | The sun and planets are a part of this system |
| 46% | SHIPWRECK | 9 | The Titanic is an example of this maritime fate |
| 45% | STRIKES | 7 | Three of these and the batter is out |
| 45% | ANTELOPE | 8 | The impala and nyala are this kind of animal |
| 43% | SAUCE | 5 | Marinara and gravy are both this type of topping |
| 43% | COMPUTERS | 9 | Cyberphobia is the fear of technology and these |
| 43% | SHELLS | 6 | Conchology is the study of molluscs and these |
| 42% | ACRONYM | 7 | Sonar and laser are examples of this |
| 42% | WATERWAYS | 9 | Rivers and canals are examples of these |
| 42% | MONSTERS | 8 | Krakens and minotaurs are examples of these |
| 42% | ELMO | 4 | This saint is the patron of sailors — and also of abdominal pain |
| 42% | EDEN | 4 | The garden of ___ is fabled to be where Adam and Eve lived |
| 42% | STIRRUP | 7 | Three bones of the ear are hammer, anvil and this |
| 42% | MEL | 3 | Blanc who was the voice of both Tweety and Sylvester |
| 42% | LIGHTNING | 9 | Chaac was the Maya god of rain, water and this |
| 42% | PLANT | 5 | Flower and tree are examples of this lifeform |
| 41% | ASONE | 5 | "... and the world will live ___" (end of the song "Imagine"): 2 wds. |
| 41% | NUCLEARFAMILY | 13 | Members of this can be found in the centers of 17-, 24-, 51- and 60-Across |
| 41% | TESS | 4 | Character name on both "This Is Us" and "The Last of Us" |
| 41% | JOHNOFARRELL | 12 | Author of the novels This Is Your Life and May Contain Nuts |
| 41% | DESSERTS | 8 | Cheesecake and ice cream are examples of these |
| 41% | TREE | 4 | Plant that provides shade... examples of which are found at the starts of 17a, 30a, and 41a |
| 40% | PAIR | 4 | The queen of hearts and the queen of spades, for example |
| 40% | ISLE | 4 | Mallorca, Bermuda and St Thomas are examples of this |
| 40% | PEARSONS | 8 | Family that's at the heart of "This Is Us" |
| 40% | HOTELS | 6 | Hilton, Hyatt, and Marriott are examples of these |