| 100% | PRIME | 5 | The largest known one is 23,249,425 digits long |
| 53% | PRIME | 5 | The largest known one is 2^(82,589,933) - 1 |
| 38% | APE | 3 | The largest arboreal animal is one |
| 37% | ARTERY | 6 | The aorta is a large one |
| 37% | MAP | 3 | The oldest known one was found carved into a mammoth tusk (~25,000 B.C.) |
| 37% | MALL | 4 | The largest one in the U.S. is in Bloomington, Minn. |
| 36% | TREE | 4 | The oldest known living one is named Methuselah |
| 36% | ORGAN | 5 | The skin is the body's largest one |
| 36% | INSIDER | 7 | One who knows how the sausage is made |
| 36% | LUNG | 4 | A human's right one is larger than the left one |
| 35% | ORGAN | 5 | Skin is the largest one |
| 35% | BONE | 4 | The femur is the longest one in the human body |
| 35% | SOAPOPERA | 9 | The longest one, Coronation Street, has been running since 1960 |
| 35% | OPAL | 4 | Olympic Australis is the world's largest one |
| 35% | RHINOCEROS | 10 | The White ___, one of the largest terrestrial animals on the planet that is known for its large horn |
| 34% | AGE | 3 | 122 is the highest known one for a human |
| 34% | BIRD | 4 | One word in the 10 longest answers, if one letter is changed |
| 34% | SLOGANS | 7 | Just Do It' is one of the most widely known |
| 34% | PSALM | 5 | The 119th one is the longest chapter of the Bible |
| 34% | VERSE | 5 | Esther 8:9 is the longest one in the Bible |
| 34% | EEL | 3 | The slender giant moray is the longest one |
| 33% | ARTERY | 6 | The aorta is the largest one in the body |
| 33% | TREE | 4 | General Sherman, in Tulare County, Calif., is the world's largest one |
| 33% | BIGTOE | 6 | On the Statue of Liberty, this digit is over four feet long |
| 33% | ASPEN | 5 | The world's largest organism by mass, known as Pando, is this type of tree |
| 33% | OPRAH | 5 | One of the most influential Americans, who is known as "The Queen of All Media" |
| 32% | EAR | 3 | A mantis is the only animal known to have just one of these |
| 32% | KOI | 3 | ___ Fish, decorative pond fish which is one of the longest living pet fish |
| 32% | SEER | 4 | If you were one, you'd already know the answer to this clue |
| 32% | HUMPBACK | 8 | The __ whale is one of the largest whale species |