| 100% | SMITHERS | 8 | The name of the butler who works for the Lodge family in "Archie" comics |
| 43% | ANDREA | 6 | ___ Bocelli, "Sacred Arias" tenor who performed for the royal family of Serbia in 2013 |
| 41% | TREO | 4 | Name of the dog that received the Dickin Medal in 2010 for work in uncovering IEDs in Afghanistan |
| 41% | PAPA | 4 | Nickname of the 1954 Nobel winner for literature, who first picked up the name in Pamplona, Spain |
| 39% | ARI | 3 | The name of the one who’s gonna last, in “Thank U, Next” |
| 39% | BOOT | 4 | Surname for a wizarding family in the "Harry Potter" universe that is also the name for a type of winter footwear |
| 39% | SCOTTWOLF | 9 | "Party of Five" actor who's doing charity work for the Elizabeth Taylor AIDS Foundation in Malawi: 2 wds. |
| 39% | SHEEN | 5 | Mr. ___, animated mascot for a cleaning brand of the same name who debuted in the late '50s |
| 38% | STOP | 4 | "___! In the Name of Love" (hit song for the Supremes) |
| 38% | SHELBY | 6 | Name of the central family in Peaky Blinders |
| 38% | NEWPLACE | 8 | Name of the Shakespeares' family home in Stratford |
| 38% | TREA | 4 | Shortstop Turner of the Nationals who hit for the cycle in both 2017 and 2019 |
| 38% | AMOS | 4 | Cedric Diggory's quite immodest dad who works in the Department for the Regulation and Control of Magical Creatures in the Harry Potter series |
| 38% | BRANT | 5 | Betty who works at the Daily Bugle in Spider-Man comics |
| 38% | VERONICA | 8 | ___ Lodge, one of Archie's love interests in Archie Comics |
| 37% | ROY | 3 | Last name of the family in "Succession" |
| 37% | ONO | 3 | Palindromic name of the musician who was awarded the ASCAP Harry Chapin Humanitarian Award in 2013 |
| 37% | REESE | 5 | Name of the six sons who inherited the peanut butter candy company in 1956 |
| 37% | ARTHURASHKIN | 12 | American scientist who won one half of the 2018 Nobel Prize in Physics for his work on optical tweezers: 2 wds. |
| 37% | VONTRAPP | 8 | Name of the musical family in The Sound of Music |
| 37% | PARR | 4 | Last name of the family in "Incredibles 2" |
| 37% | BANKS | 5 | Last name of the family in "Mary Poppins Returns" |
| 37% | BAGGINS | 7 | Family name of Bilbo in The Hobbit |
| 37% | MONTAGUE | 8 | Family name of Romeo in the play |
| 36% | INABSENTIA | 10 | How Paul Hofmann, who worked for the NYT, was tried in Italy in 1944 |
| 36% | RADCLIFFE | 9 | Last name of the actor who was the titular protagonist in "Harry Potter" series |
| 36% | LARASTHEME | 10 | Informal name of the instrumental music written for the character played by 33-Across in "Doctor Zhivago" (2 wds.) |
| 36% | COOPERKUPP | 10 | 2021 NFL Offensive Player of the Year who caught two touchdown passes in the 2022 Super Bowl for 21-Across and was named Super Bowl MVP (2 wds.) |
| 36% | PIE | 3 | "Sedgwick ___": the name of the Sedgwick family's burial plot in Stockbridge Cemetery, Stockbridge, MA |
| 36% | GEORGEPSMITH | 12 | American biologist who shared one half of the 2018 Nobel Prize in Chemistry with Gregory P. Winter, for work on phage display: 3 wds. |