| 100% | BUSTS | 5 | The Napoleons in the Sherlock Holmes story "The Adventure of the Six Napoleons" |
| 62% | PIKE | 4 | Langdale ___, gossipmonger in the Sherlock Holmes stories who is introduced in "The Adventure of the Three Gables" |
| 53% | BAND | 4 | "The Adventure of the Speckled ___," Sherlock Holmes short story by Arthur Conan Doyle |
| 53% | BLUE | 4 | "The Adventure of the ___ Carbuncle," Sherlock Holmes story that is set around Christmas |
| 52% | BRETT | 5 | Jeremy —, actor who played the title role in 1980s ITV drama series The Adventures of Sherlock Holmes |
| 51% | IRENE | 5 | Adler of the Sherlock Holmes story “A Scandal in Bohemia” |
| 50% | POISOND | 7 | Cause of death in the Sherlock Holmes novel "The Sign of the Four" |
| 50% | ZUCCO | 5 | George —, Manchester-born actor who played Professor Moriarty in 1939 film drama The Adventures of Sherlock Holmes |
| 47% | MORIARTY | 8 | Sherlock Holmes' adversary, the Napoleon of Crime |
| 46% | NIGEL | 5 | Actor Bruce who played Watson in "The New Adventures of Sherlock Holmes" |
| 46% | JUDELAW | 7 | Costar of Robert Downey, Jr. in the Sherlock Holmes films: 2 wds. |
| 45% | MARY | 4 | ___ Morstan, Watson's wife in the Sherlock Holmes stories who was played by Amanda Abbington on screen |
| 43% | SHOES | 5 | One of the six words in Hemingway’s apocryphal six-word story |
| 43% | STEPHENS | 8 | Robert —, actor who played the title role in 1970 comedy-adventure film The Private Life of Sherlock Holmes |
| 42% | FINAL | 5 | & 16A The —, Sherlock Holmes story by Arthur Conan Doyle first published in the Strand Magazine in December 1893 |
| 42% | COOK | 4 | Peter ___, actor who played Sherlock Holmes in the 1978 British film "The Hound of the Baskervilles" |
| 41% | MORIARTY | 8 | Professor James —, arch-enemy of Sherlock Holmes in stories by Arthur Conan Doyle |
| 40% | RAPACE | 6 | Noomi —, actress who played Madam Simza Heron in 2011 adventure film Sherlock Holmes: A Game of Shadows |
| 40% | IRENEADLER | 10 | Woman in a Sherlock Holmes story |
| 40% | IRENE | 5 | Adler of the “Sherlock Holmes” stories |
| 40% | IRENEADLER | 10 | Fictional opera singer/actress who outsmarts Sherlock Holmes in the Arthur Conan Doyle story "A Scandal in Bohemia" (2 wds.) |
| 40% | RAPACE | 6 | Noomi —, Swedish actress who played Madam Simza Heron in 2011 adventure film Sherlock Holmes: A Game of Shadows |
| 39% | BAKERSTREET | 11 | & 1A Group of street urchins who aid Sherlock Holmes in various stories by Arthur Conan Doyle |
| 38% | IRENE | 5 | Woman in Sherlock Holmes stories |
| 38% | IRENE | 5 | Adler in Sherlock Holmes stories |
| 38% | IRENE | 5 | Adler of Sherlock Holmes stories |
| 38% | ADLER | 5 | Irene of a Sherlock Holmes story |
| 38% | IRENE | 5 | ___ Adler (woman in Sherlock Holmes stories) |
| 38% | ADLER | 5 | Irene ___, figure in Sherlock Holmes stories |