| 100% | CANAL | 5 | The Panama ___ |
| 90% | CANAL | 5 | The Panama ___ (ocean-connecting waterway) |
| 85% | COLON | 5 | Port on the Panama Canal |
| 85% | SIESTAS | 7 | Breaks along the Panama Canal? |
| 85% | APLAN | 5 | Part of the Panama palindrome |
| 83% | ZONESHOT | 8 | Photo of the Panama Canal, once? |
| 81% | CANAL | 5 | Waterway such as the Panama or Erie |
| 81% | STEAMSHOVELS | 12 | Machines used to dig the Panama Canal |
| 80% | ANA | 3 | The Panama C___l made travel for ships much easier |
| 79% | BLAS | 4 | Gulf of San ___, east of the Panama Canal |
| 78% | CANALS | 6 | Artificial waterways such as the Panama and the Suez |
| 77% | ANCON | 5 | SS ___ (first ship to pass through the Panama Canal) |
| 73% | CANAL | 5 | Waterway such as the Suez or Panama |
| 69% | CARGOSHIPS | 10 | Most vessels passing through the Suez and Panama Canals |
| 69% | CANALS | 6 | The Suez and the Panama, for example |
| 67% | ANA | 3 | Good "Wheel of Fortune" purchase for the answer PANAMA CANAL |
| 67% | CULEBRACUT | 10 | Artificial valley linking Gatun Lake to the Bay of Panama |
| 65% | SANBLAS | 7 | — Islands, archipelago off the north coast of the Isthmus of Panama |
| 64% | BALBOA | 6 | Official currency of Panama along with the US dollar |
| 63% | LEIGH | 5 | ___ Mercer, originator of the palindrome "A man, a plan, a canal - Panama!" |
| 59% | ISTHMUS | 7 | Narrow strip of land connecting two larger land areas, such as the — of Panama |
| 55% | NORIEGA | 7 | Military strongman and longtime C.I.A. informant captured during the U.S. invasion of Panama |
| 51% | MANUEL | 6 | Panama's Noriega who was captured in 1990 as a result of the Navy SEALs' Operation Nifty Package |
| 49% | CANAL | 5 | Panama ____ |
| 49% | STRAWHAT | 8 | Panama |
| 48% | DEFINITEARTICLE | 15 | The |
| 47% | FIESTA | 6 | Panama party |
| 47% | HATCHECK | 8 | Panama claim |
| 47% | ISTHMUS | 7 | Panama landform |
| 47% | BALBOA | 6 | Panama port |