| 100% | URACIL | 6 | The RNA nucleobase replaced by thymine in DNA |
| 41% | MALTESELIRA | 11 | Currency replaced by the euro in 2008 |
| 41% | LIRE | 4 | Currency replaced by the euro in Italy |
| 41% | TOLAR | 5 | Currency replaced by the euro in Slovenia |
| 40% | SANDS | 5 | Vegas casino replaced by the Venetian in 1999 |
| 39% | MRS | 3 | ___ White (character replaced by Dr. Orchid in the game Clue) |
| 39% | AUSTRAL | 7 | Standard monetary unit of Argentina replaced by the peso in 1992 |
| 39% | NAFTA | 5 | Pact replaced by the U.S.M.C.A. in 2020 |
| 38% | INTI | 4 | Standard unit of currency of Peru replaced by the nuevo sol in 1991 |
| 37% | ESCUDO | 6 | Gold coin originally worth 16 silver reais and replaced by the euro in the 1990s |
| 36% | LATS | 4 | Standard unit of currency of Latvia replaced in 2014 by the Euro |
| 35% | ELIDED | 6 | Like the "f" replaced by an apostrophe in "man-o'-war" |
| 33% | IRISHPOUND | 10 | One of the currencies replaced by the euro in 2002 |
| 33% | VARIABLE | 8 | In the answers to 17-, 34- and 57-Across, it was replaced in turn by 1, 2, 3, 4, 5 ... |
| 32% | BADGUY | 6 | 2019 song by Billie Eilish which reached number one in the Billboard Hot 100 replacing 27a: 2 wds. |
| 32% | URACIL | 6 | Thymine : DNA :: ___ : RNA |
| 32% | ADENINE | 7 | Base in DNA and RNA |
| 32% | ACID | 4 | "A" in DNA or RNA |
| 32% | PESETA | 6 | Coin replaced by the euro |
| 32% | LIRA | 4 | Money replaced by the euro |
| 32% | FRANC | 5 | Currency replaced by the euro |
| 32% | LIRE | 4 | Money replaced by the euro |
| 32% | LIRA | 4 | Coin replaced by the euro |
| 32% | LIRA | 4 | Currency replaced by the euro |
| 32% | ESCUDO | 6 | Currency replaced by the euro |
| 32% | PESETA | 6 | Currency replaced by the euro |
| 32% | PAGER | 5 | Device replaced by the cellphone |
| 32% | IRISHPOUND | 10 | *Currency replaced by the euro |
| 32% | NAFTA | 5 | Pact replaced by the USMCA |
| 32% | MARK | 4 | Currency replaced by the euro |