| 100% | REESE | 5 | The second-oldest brother on "Malcolm in the Middle" |
| 99% | REESE | 5 | One of Malcolm's older brothers on "Malcolm in the Middle" |
| 93% | REESE | 5 | Older brother of Malcolm on "Malcolm in the Middle" |
| 79% | REESE | 5 | One of the brothers on "Malcolm in the Middle" |
| 77% | REESE | 5 | Brother of Malcolm on "Malcolm in the Middle" |
| 72% | HAL | 3 | Malcolm's dad on "Malcolm in the Middle" |
| 72% | HAL | 3 | Malcolm's father on "Malcolm in the Middle" |
| 72% | LOIS | 4 | Malcolm's mother on "Malcolm in the Middle" |
| 72% | HAL | 3 | Malcolm's father, on "Malcolm in the Middle" |
| 67% | FRANKIEMUNIZ | 12 | Actor who played child prodigy Malcolm on "Malcolm in the Middle": 2 wds. |
| 66% | LOIS | 4 | Mom on "Malcolm in the Middle" |
| 66% | HAL | 3 | Dad on "Malcolm in the Middle" |
| 64% | MUNIZ | 5 | Frankie who starred on "Malcolm in the Middle" |
| 64% | HAL | 3 | Lois's husband on "Malcolm in the Middle" |
| 64% | HAL | 3 | Lois's husband, on "Malcolm in the Middle" |
| 64% | HAL | 3 | Bryan Cranston's role on "Malcolm in the Middle" |
| 64% | HAL | 3 | Bryan Cranston's character, on "Malcolm in the Middle" |
| 61% | BOSS | 4 | "___ of Me" (They Might Be Giants song featured on "Malcolm in the Middle") |
| 60% | TITO | 4 | Second-oldest brother in the Jackson 5 |
| 60% | OHIO | 4 | Answer to the old riddle "What's round on the sides and high in the middle?" |
| 60% | OHIO | 4 | Answer to the old riddle "What's round on the ends and high in the middle?" |
| 56% | TWIXT | 5 | In the middle of, old-style |
| 56% | TANIA | 5 | Actress Raymonde of Lost and Malcolm in the Middle |
| 56% | CRANSTON | 8 | Breaking Bad and Malcolm in the Middle star Bryan |
| 56% | ESAU | 4 | Older brother of Jacob, in the Bible |
| 56% | CAIN | 4 | Elder brother of Seth, in the Bible |
| 55% | IRAN | 4 | Second-largest country in the Middle East, after Saudi Arabia |
| 54% | FRANKIEMUNIZ | 12 | "Malcolm in the Middle" actor who was a finalist on season 25 of "Dancing with the Stars" (2 wds.) |
| 54% | SAG | 3 | Dip in the middle, like an old mattress |
| 54% | SAG | 3 | Droop in the middle, as an old sofa |