| 100% | SYS | 3 | The second "S" in MS-DOS, for short |
| 71% | SYS | 3 | The second "S" in MS-DOS: Abbr. |
| 71% | SYS | 3 | "S" in MS-DOS, for short |
| 69% | SYS | 3 | The "S" in DOS, for short |
| 64% | SYS | 3 | The "S" of MS-DOS, for short |
| 64% | SYS | 3 | The S in GPS, for short |
| 59% | SERVICE | 7 | The second S in SMS messaging |
| 58% | STD | 3 | The "S" in EST, for short |
| 58% | SYS | 3 | The "S" in GPS, for short |
| 58% | SYS | 3 | The "S" in iOS, for short |
| 58% | SYS | 3 | The "S" in OS, for short |
| 58% | SYS | 3 | The "S" in macOS, for short |
| 58% | SYS | 3 | The "S" in 7a, for short |
| 58% | SYS | 3 | The "S" in 1a, for short |
| 58% | SCI | 3 | The "S" in STEM, for short |
| 58% | SAT | 3 | The "S" in SNL, for short |
| 58% | STD | 3 | The "S" in PST, for short |
| 58% | SYS | 3 | The "S" in iPadOS, for short |
| 58% | SCI | 3 | The "S" in STEM. for short |
| 58% | STD | 3 | The "S" in CST, for short |
| 58% | SOC | 3 | The "S" in ASCAP, for short |
| 58% | STUPID | 6 | The second S in KISS, "keep it simple, __" |
| 55% | SYST | 4 | The second "S" of MS-DOS: Abbr. |
| 55% | AUG | 3 | Alphabetically it's the second month, for short |
| 54% | SPRINT | 6 | It's done in the short run |
| 54% | SYS | 3 | "S" in DOS, for short |
| 52% | SCLEROSIS | 9 | S in the immune system disease MS |
| 51% | PAN | 3 | Flash in the ___ (something that's popular for a short time) |
| 51% | USAF | 4 | The Thunderbirds are in it, for short |
| 50% | HRS | 3 | The two dozen in a day, for short |