| 100% | SEWANEE | 7 | The University of the South, familiarly |
| 82% | SEWANEE | 7 | The University of the South, commonly |
| 78% | APIA | 4 | Capital with the University of The South Pacific |
| 70% | BEND | 4 | South ___, Indiana (city near the University of Notre Dame) |
| 69% | FURMAN | 6 | University dubbed "The Country Club of the South" |
| 68% | SEWANEE | 7 | Home of the University of the South |
| 67% | JOHANNESBURG | 12 | City in Gauteng, South Africa, housing the University of Witwatersrand |
| 66% | REBEL | 5 | ___ Wilson, "Pitch Perfect" actress with a law degree from the University of New South Wales |
| 66% | SEWANEE | 7 | Home and nickname of The University of the South |
| 65% | STELLENBOSCH | 12 | University town in Western Cape, South Africa, on the banks of the Eerste River |
| 65% | SUVA | 4 | Main campus site of the University of the South Pacific |
| 65% | LIMA | 4 | Site of the oldest university in South America |
| 64% | OLE | 3 | ___ Miss (the University of Mississippi, familiarly) |
| 62% | BANGOR | 6 | University city in NW Wales on the south shore of the Menai Strait |
| 61% | GLINDA | 6 | The Witch of the South |
| 60% | PALOALTO | 8 | US city south-east of San Francisco near the seat of Stanford University |
| 60% | STEVESPURRIER | 13 | Former NFL coach who coached the University of South Carolina football team from 2005 to 2015 (2 wds.) |
| 59% | ALIYAHBOSTON | 12 | University of South Carolina power forward/center who was honored with the 2022 Wade Trophy (2 wds.) |
| 58% | UCONN | 5 | The Huskies of the NCAA, familiarly |
| 58% | OLEMISS | 7 | The Rebels of the SEC, familiarly |
| 58% | ATLANTA | 7 | City dubbed the Hollywood of the South |
| 57% | HOGS | 4 | University of Arkansas athletes, familiarly |
| 57% | VOL | 3 | University of Tennessee athlete, familiarly |
| 57% | TERPS | 5 | University of Maryland athletes, familiarly |
| 57% | DAWG | 4 | University of Georgia athlete, familiarly |
| 57% | DAWGS | 5 | University of Georgia athletes, familiarly |
| 57% | SAOPAULO | 8 | Brazilian city dubbed the Paris of the South |
| 57% | ATL | 3 | City nicknamed the "Hollywood of the South": Abbr. |
| 57% | ROANOKE | 7 | The Star City of the South |
| 56% | ORONO | 5 | The University of Maine’s hometown |