| 100% | THOUSAND | 8 | This is the first number to have the letter "A" |
| 67% | HAYES | 5 | First president to have a phone in the White House—its number was "1" (1877) |
| 60% | DOMEE | 5 | Shi who was the first woman to have the sole director’s credit on a Pixar feature, for “Turning Red” |
| 60% | USN | 3 | JFK was the first president to have served in this branch of the US Armed Forces |
| 58% | NONET | 5 | A chamber work by Louis Spohr was the first to bear this title |
| 58% | GEHRIG | 6 | Yankee who was the first major-leaguer to have his number retired |
| 57% | MADAMSPEAKER | 12 | *Nancy Pelosi was the first person ever to have this title in Congress |
| 57% | TEN | 3 | The first number to have two digits |
| 57% | USA | 3 | This nation's athlete is the first figure skater to land eight quads in a competition |
| 57% | JENNA | 5 | Marbles who is the first social-media star to have a wax statue at Madame Tussauds |
| 56% | SWOOPES | 7 | Sheryl who was the first W.N.B.A. player to have a signature shoe |
| 56% | EAR | 3 | A mantis is the only animal known to have just one of these |
| 56% | DOG | 3 | President Trump is the first president in over 100 years not to have one of these |
| 54% | ECLAIR | 6 | Pastry that becomes a name when the first letter is moved to the end |
| 54% | THEOTHERAMERICA | 15 | Read the first letter in each clue to get a quote from this '67 speech |
| 54% | YOUNG | 5 | The Stingray Nebula has to be considered this, as far a nebulae go |
| 53% | WIN | 3 | Be the first one to finish a race, say |
| 53% | LORNASIMPSON | 12 | "Projects 23" photographer who was the first African-American woman to have a solo exhibition at the Museum of Modern Art (2 wds.) |
| 53% | EGG | 3 | The hundred folds on a chef's toque are said to represent the number of ways to prepare this |
| 52% | THROWACURVEBALL | 15 | Candy Cummings was the first pitcher to do this |
| 52% | TEBOW | 5 | Tim who was the first sophomore to win a Heisman |
| 51% | ULRIC | 5 | German prelate who was the first person to be canonized, A.D. 993 |
| 51% | LORRE | 5 | Peter who was the first actor to play a Bond villain |
| 51% | IRA | 3 | Songwriter Gershwin who was the first lyricist to win a Pulitzer |
| 51% | OLEG | 4 | Man's name that becomes a toy when its first letter is moved to the end |
| 51% | ELAYNE | 6 | Boosler who was the first woman to have an hour-long comedy special on cable TV |
| 51% | ANG | 3 | Lee who was the first Asian to win a best-director Oscar |
| 51% | HINDU | 5 | Rishi Sunak was the first one to become a British prime minister |
| 51% | OSE | 3 | Monosaccharides are named according to a Greek prefix to indicate the number of carbon atoms followed by this suffix, meaning "sugar" |
| 50% | HAYES | 5 | First president to have a telephone in the White House |