| 100% | ESSES | 5 | Three letters in ''sisters'' |
| 82% | EMS | 3 | Three letters in ''mammoth'' |
| 82% | EMS | 3 | Three letters in ''mommy'' |
| 82% | ENS | 3 | Three letters in ''nanny'' |
| 82% | ESSES | 5 | Three letters in ''discuss'' |
| 82% | ESSES | 5 | Three letters in ''lasses'' |
| 82% | ESSES | 5 | Three letters in ''guesses'' |
| 82% | EMS | 3 | Three letters in "mommy" |
| 82% | ENS | 3 | Three letters in "nanny" |
| 77% | DOTTED | 6 | Like three letters in this clue |
| 76% | TCB | 3 | Three letters in the logo & motto of Elvis Presley |
| 75% | ETC | 3 | Last three letters in a list, often |
| 75% | ABC | 3 | First three letters in a kindergarten tune |
| 71% | STU | 3 | Name that's three letters in a row in the alphabet |
| 70% | EYE | 3 | Three letters to describe the opening in a needle |
| 70% | EUR | 3 | Three letter code for the currency spent in France |
| 67% | SIC | 3 | Latin three letters to mark an error in writing |
| 65% | CHARMED | 7 | Three sister witches fight evil in this TV show |
| 65% | PSI | 3 | Three-point letter you won't find in Scrabble? |
| 64% | ETA | 3 | First letter in the Greek alphabet whose name is three letters long |
| 63% | THEBIGAPPLE | 11 | Empire State Building locale ... or a hint to three letters in 16-, 19-, 52- and 57-Across |
| 63% | MASHA | 5 | Sister in "Three Sisters" |
| 62% | YEAR | 4 | Span represented by the first three letters of 12 answers in this puzzle |
| 62% | CHEKHOV | 7 | He wrote a play about three sisters in 1901 |
| 62% | IKEA | 4 | Store with a three-syllable name in four letters |
| 62% | STU | 3 | Guy found in three consecutive letters of the alphabet |
| 60% | ESP | 3 | Sixth sense, in three letters |
| 60% | SOONG | 5 | Last name of three prominent sisters in 20th-century Chinese history |
| 59% | MTN | 3 | PepsiCo used these three letters in 2008 to rebrand the soft drink that now offers Pitch Black as a flavor |
| 59% | PEA | 3 | "A seed with three letters in my name. Take away two and I still sound the same. What am I?" |