| 100% | GOLDBERGS | 9 | Title family in a 2013-23 ABC sitcom |
| 63% | DHARMA | 6 | Title character in a new 1997 ABC sitcom |
| 48% | ADO | 3 | Word in a 2013 Joss Whedon film title |
| 48% | MOESHA | 6 | Title teen in a 1990s sitcom |
| 48% | ALLIE | 5 | Title role in a 1980s sitcom |
| 47% | HOGAN | 5 | Title colonel in a 1960's sitcom |
| 47% | ALLIE | 5 | Title character in a 1980's sitcom |
| 47% | ALF | 3 | Title alien in a 1986-1990 sitcom |
| 47% | JEANNIE | 7 | Title role in a nineteen-sixties sitcom |
| 45% | DONNAREED | 9 | She played Donna Stone in a classic ABC sitcom |
| 44% | THEGOLDBERGS | 12 | ABC sitcom about a geeky boy growing up in the 1980s: 2 wds. |
| 42% | ALLIE | 5 | ___ Lowell, title character in a 1980's sitcom |
| 41% | TRUMPETS | 8 | 2013 song by Jason Derulo with a brass instrument in its title |
| 41% | HANNAH | 6 | "___ Montana," Disney sitcom with a palindromic name in the title |
| 41% | LLEWYN | 6 | ___ Davis (title role in a 2013 Coen brothers film) |
| 41% | DRAKEANDJOSH | 12 | *Title pair in a 2004-07 Nickelodeon sitcom |
| 41% | THEWONDERYEARS | 14 | 1988-1993 family sitcom rebooted in 2021 for ABC: 3 wds. |
| 40% | SUBURGATORY | 11 | Former ABC sitcom, about life in a town outside New York City, that featured Alan Tudyk |
| 40% | OHARAS | 6 | Family in a 1936 novel |
| 40% | DORRITS | 7 | Family in a Dickens novel |
| 40% | SIMS | 4 | Family in a computer game |
| 40% | OHARA | 5 | Family in a 1939 movie |
| 40% | BEETHOVEN | 9 | Title St. Bernard in a 1992 family comedy film |
| 40% | ALF | 3 | Gordon Shumway's title alias, in a sitcom |
| 39% | OHARAS | 6 | Family in a 1936 best seller |
| 39% | ONEDAYATATIME | 13 | 1975-1984 Bonnie Franklin sitcom with a number in its title: 5 wds. |
| 39% | THREESCOMPANY | 13 | 1977-1984 Suzanne Somers sitcom with a number in its title: 2 wds. |
| 39% | ILOVELUCY | 9 | Classic sitcom whose title was written in cursive over a heart (3 wds.) |
| 39% | BRADYBUNCH | 10 | "The ___," ABC sitcom about a large blended family with six children that ran from 1969 - 1974: 2 wds. |
| 39% | KRAMERS | 7 | Family in a 1979 Oscar-winning film |