| 100% | MAGUIRE | 7 | Tobey, who played Spider-Man in 2002 |
| 73% | TOBEY | 5 | Maguire who first played Spider-Man in 2002 |
| 68% | TOBEYMAGUIRE | 12 | Actor who plays Spider-Man in Sam Raimi's "Spider-Man" trilogy (2002, 2004, 2007) (2 wds.) |
| 67% | TOM | 3 | Holland who played Spider-Man in "Avengers: Infinity War" |
| 66% | TOMHOLLAND | 10 | Actor who plays Spider-Man in 16-Across: 2 wds. |
| 66% | ANDREW | 6 | Actor ___ Garfield who played Spider-Man in "The Amazing Spider-Man" |
| 64% | TOBEY | 5 | ___ Maguire, actor who played Spider-Man in Sam Raimi's "Spider-Man" trilogy |
| 63% | TOM | 3 | ___ Holland, actor who plays Spider-Man in Marvel's "Spider-Man: No Way Home" |
| 63% | TOBEYMAGUIRE | 12 | Actor who plays Spider-Man in Sam Raimi's "Spider-Man" trilogy (2 wds.) |
| 62% | TOMHOLLAND | 10 | Actor from "The Impossible" who plays Spider-Man in the upcoming "Spider-Man: Homecoming": 2 wds. |
| 61% | ANDREWGARFIELD | 14 | Actor who plays Spider-Man in Marc Webb's two "The Amazing Spider-Man" films (2 wds.) |
| 60% | ANDREW | 6 | ___ Garfield, actor who played Spider-Man in the 2012 film "The Amazing Spider-Man" and its 2014 sequel |
| 60% | ANDREWGARFIELD | 14 | Actor who plays Spider-Man in Marc Webb's two "The Amazing Spider-Man" films (2012, 2014) (2 wds.) |
| 59% | JAMIE | 5 | Foxx who played Electro in “The Amazing Spider-Man 2” |
| 59% | FOXX | 4 | Actor Jamie who played Electro in "The Amazing Spider-Man 2" |
| 58% | ZENDAYA | 7 | One-named Disney Channel star who played MJ in Spider-Man: Homecoming |
| 57% | TOMHOLLAND | 10 | Actor who plays Spider-Man in Jon Watts's "Spider-Man: Homecoming" and "Spider-Man: Far from Home" (2017, 2019) (2 wds.) |
| 57% | MARISA | 6 | Tomei who plays May Parker in Spider-Man movies |
| 56% | DENIS | 5 | Leary who played George Stacy in two Spider-Man films |
| 55% | TOMHOLLAND | 10 | Actor who plays Spider-Man in Jon Watts's "Spider-Man: Homecoming," "Spider-Man: Far from Home," and "Spider-Man: No Way Home" (2 wds.) |
| 55% | HAMM | 4 | Jon who played Don in "Mad Men" |
| 55% | TOBEY | 5 | Maguire who played Spider-Man |
| 55% | TOM | 3 | "Spider Man: Homecoming" star Holland who got his start playing Billy Elliot onstage in London |
| 55% | TOM | 3 | Holland who plays Spider-Man |
| 54% | ROBERTDOWNEYJR | 14 | Actor who plays Iron Man in "Avengers: Endgame" (3 wds.) |
| 54% | MICHAEL | 7 | ___ Keaton, who plays Vulture in "Spider-Man: Homecoming" |
| 54% | CHEADLE | 7 | Don who plays Rhodey in Iron Man movies |
| 54% | TOM | 3 | Actor Holland who plays Spider-Man |
| 54% | HOLLAND | 7 | Actor Tom who plays Spider-Man |
| 54% | SYDNEYSWEENEY | 13 | "Euphoria" actress who plays Spider-Woman in "Madame Web" (2 wds.) |