| 100% | UHURA | 5 | U.S.S. Enterprise officer played by Nichelle Nichols and Zoe Saldana |
| 75% | UHURA | 5 | "Star Trek" officer played by Nichelle Nichols and Zoe Saldana |
| 68% | UHURA | 5 | "Star Trek" character who's been played by Nichelle Nichols and Zoe Saldana |
| 65% | UHURA | 5 | "Star Trek" role played by Nichelle Nichols and Zoe Saldana |
| 53% | UHURA | 5 | Communications officer aboard the USS Enterprise originally played by Nichelle Nichols |
| 44% | UHURA | 5 | "Star Trek" officer originally played by Nichelle Nichols |
| 41% | UHURA | 5 | Role for Nichelle Nichols and Zoë Saldana |
| 40% | UHURA | 5 | Classic role for Nichelle Nichols and Zoë Saldana |
| 37% | UHURA | 5 | "Star Trek" character played by Nichelle Nichols |
| 36% | LIEUTENANTUHURA | 15 | “Star Trek” communications officer portrayed by Nichelle Nichols |
| 36% | UHURA | 5 | "Star Trek" role first played by Nichelle Nichols |
| 36% | UHURA | 5 | "Star Trek" character first played by Nichelle Nichols |
| 33% | CDR | 3 | U.S.S. Enterprise officer: Abbr. |
| 32% | KELLYGRAYSON | 12 | Commander and first officer played by Adrianne Palicki on 49-Across (2 wds.) |
| 32% | GAMORA | 6 | Green "Avengers: Infinity War" character played by Zoe Saldana |
| 30% | UHURA | 5 | U.S.S. Enterprise's resident linguist and cryptographer |
| 29% | REBECCA | 7 | ___ Pearson, mother to Kevin, Kate, and Randall on "This Is Us," played by Mandy Moore |
| 28% | THEPENGUIN | 10 | Batman foe who’s been played by Danny DeVito and Colin Farrell |
| 28% | OHIOAN | 6 | U. S. Grant, by birth |
| 27% | ALEUTIANS | 9 | Chain owned by Russia and the U.S. |
| 27% | POPPY | 5 | 1982 stage play by Peter Nichols |
| 27% | APRILDANCER | 11 | TV's "Girl from U.N.C.L.E.," played by Stefanie Powers |
| 27% | SULU | 4 | "Star Trek" officer played by John Cho |
| 27% | IRIS | 4 | Role played by both Kate and Judi |
| 27% | CARRIE | 6 | First name of 18-Across's little sister, played by Lindsay and Sidney Greenbush |
| 27% | NINASIMONE | 10 | Singer played by Zoe Saldaña in a 2016 musical biopic (2 wds.) |
| 26% | WIGHTMAN | 8 | Former women's tennis cup played between US and GB |
| 26% | NORAD | 5 | Military org. run jointly by the U.S. and Canada |
| 26% | PIANO | 5 | Instrument played by Elton John and Billy Joel |