| 100% | WALES | 5 | United Kingdom setting for the BBC sci-fi series "Torchwood" |
| 44% | GMT | 3 | Clock setting for the BBC |
| 40% | BABYLON5 | 8 | Sci-fi series set in the 23rd century |
| 39% | DOCTORWHO | 9 | BBC sci-fi series in which 31-Across plays the 10th and 14th incarnations of the title character: 2 wds. |
| 39% | STARTREK | 8 | Famous sci-fi series set on the Enterprise |
| 38% | BRITAIN | 7 | Another name for the United Kingdom |
| 38% | DRWHO | 5 | BBC sci-fi series, informally |
| 38% | WHO | 3 | BBC sci-fi series "Doctor ___" |
| 37% | GBR | 3 | Three-letter country code for the United Kingdom |
| 37% | ENYA | 4 | Composer for the BBC documentary series The Celts: Rich Traditions and Ancient Myths |
| 37% | WHO | 3 | "Doctor ___," BBC sci-fi series |
| 36% | BREXIT | 6 | Nickname for the United Kingdom's departure from the European Union |
| 36% | WHO | 3 | "Doctor ___" (long-running BBC sci-fi series) |
| 35% | EVENT | 5 | Jason Ritter sci-fi series that lasted for one season, with "The" |
| 35% | DOCTORWHO | 9 | BBC sci-fi series that debuted in 1963: 2 wds. |
| 35% | USSENTERPRISE | 13 | Setting for many sci-fi stories |
| 35% | SPACE | 5 | Setting for many sci-fi movies |
| 34% | IDRIS | 5 | & 4D London-born actor known for the title role in BBC TV series Luther |
| 34% | EXPANSE | 7 | "The ___," sci-fi TV series starring Steven Strait that is set in a future where humans colonize the Solar System |
| 34% | BRIT | 4 | Native of the United Kingdom, for short |
| 34% | TROY | 4 | Setting for the "Iliad" |
| 34% | GRANDAD | 7 | BBC TV series for children that starred Clive Dunn in the title role |
| 34% | LAYETTE | 7 | Set for the nursery |
| 34% | TEASERVICE | 10 | Set for the afternoon? |
| 34% | WEST | 4 | "The Wild Wild ___," '60s sci-fi series starring Robert Conrad that reunited the original cast for two TV reunion films |
| 33% | FARSCAPE | 8 | Sci-fi series set on a spacecraft called Moya |
| 33% | DANCEHALL | 9 | Setting for the swing set? |
| 33% | GOTHAM | 6 | Setting for the 51-Across |
| 33% | TOKYO | 5 | Setting for the original "Godzilla" |
| 33% | FARM | 4 | Setting for the film "Babe" |