| 100% | GODMODE | 7 | Video-game cheat code that grants invincibility (2 wds.) |
| 61% | THESIMS | 7 | Video game with a "rosebud" cheat code that grants free money |
| 51% | MADDENNFL | 9 | Video game franchise that featured 15-Across on the cover of the 2011 version: 2 wds. |
| 48% | AMONGUS | 7 | Video game set in space that went viral in 2020 (2 wds.) |
| 46% | DONKEYKONG | 10 | Video game with a gorilla that first featured the main character of 43-Across (2 wds.) |
| 45% | STAR | 4 | Item that grants invincibility in the Super Mario Bros. games |
| 45% | THESIMS | 7 | Video game franchise with the cheat code "rosebud" |
| 44% | SUGARRUSH | 9 | Kart-racing video game in 20-Across: 2 wds. |
| 44% | EXTRALIFE | 9 | Another chance to play, in video games: 2 wds. |
| 44% | MARIOKART | 9 | Nintendo racing video game franchise: 2 wds. |
| 42% | HEROSDUTY | 9 | First-person shooter video game in 20-Across: 2 wds. |
| 42% | WIIU | 4 | Nintendo video game console released in 2012: 2 wds. |
| 42% | MORTALKOMBAT | 12 | Fighting video game adapted into a series of films: 2 wds. |
| 41% | ANGRYBIRDS | 10 | Puzzle video game adapted into two Jason Sudeikis animated films: 2 wds. |
| 41% | RESIDENTEVIL | 12 | Survival-horror video game series, or a 2002 Milla Jovovich film: 2 wds. |
| 41% | ELDENRING | 9 | 2022 fantasy video game with material from George R.R. Martin: 2 wds. |
| 40% | SATOSHITAJIRI | 13 | Japanese video game designer who is the creator of the Pokemon franchise: 2 wds. |
| 40% | TOMBRAIDER | 10 | Adventure video game adapted into films starring Angelina Jolie and Alicia Vikander: 2 wds. |
| 40% | GHOSTRECON | 10 | Tom Clancy video game franchise about an intelligence-gathering special-ops squad: 2 wds. |
| 39% | STREETFIGHTER | 13 | Combat-based video game series, or a 1994 Jean-Claude Van Damme film: 2 wds. |
| 39% | RAINBOWSIX | 10 | Tom Clancy video game franchise about a counterterrorist unit with a colorful title: 2 wds. |
| 39% | SPLINTERCELL | 12 | Tom Clancy video game franchise about a black-ops subdivision within the NSA: 2 wds. |
| 39% | MIKETYSON | 9 | Heavyweight champ who's been featured in the "Punch-Out!!" boxing video game: 2 wds. |
| 39% | JOHNMADDEN | 10 | Legendary coach and commentator whose name is on an NFL video game series: 2 wds. |
| 39% | CHESSSETS | 9 | Game shop purchases that include boards, kings, and pawns: 2 wds. |
| 39% | DJHERO | 6 | Music video game with a turntable controller (2 wds.) |
| 39% | GARYCOLEMAN | 11 | "Diff'rent Strokes" star who appears as himself in the 2003 video game "Postal 2": wds. |
| 38% | SUPERMARIO | 10 | Video game franchise set in the Mushroom Kingdom (2 wds.) |
| 38% | NAUGHTYDOG | 10 | Video game company that created the "Uncharted" action-adventure game series, which has been adapted into a film starring Antonio Banderas, 31-Across, and 43-Across (2 wds.) |
| 38% | UNTILDAWN | 9 | Survival horror adventure video game in which Rami Malek (birthday today) appears as Josh Washington: 2 wds. |