| 100% | GTA | 3 | Video-game franchise with installments set in Vice City and San Andreas, briefly |
| 65% | GTA | 3 | Popular video-game series with versions in Vice City and San Andreas, briefly |
| 65% | GTA | 3 | Video-game franchise with Vice City and San Andreas installments, for short |
| 55% | GTA | 3 | Popular game franchise with "Vice City" and "San Andreas" installments: Abbr. |
| 53% | GTA | 3 | Video game series with settings in Liberty City and San Andreas, for short |
| 47% | GTA | 3 | Video-game franchise whose settings include Liberty City, San Andreas, and Vice City, for short |
| 45% | GTA | 3 | Video-game franchise with a San Andreas installment, for short |
| 37% | HALO | 4 | Video game franchise set in the 26th century |
| 36% | SUPERMARIO | 10 | Video game franchise set in the Mushroom Kingdom (2 wds.) |
| 36% | MARIOBROS | 9 | Video game franchise with characters found at the ends of 17-, 20-, 53- and 58-Across |
| 36% | AUTO | 4 | "Grand Theft ___ V," one of the best-selling video games released in 2013 that is set in the fictional state of San Andreas |
| 35% | GTA | 3 | Game set in Liberty City, briefly |
| 35% | GRANDTHEFTAUTO | 14 | With 42-Across, 2001 video game set in Liberty City |
| 34% | SEGA | 4 | Video game company with the After Burner and Virtua Fighter franchises |
| 34% | BIOSHOCK | 8 | 2007 video game with Jack in an underwater city |
| 34% | TOMBRAIDER | 10 | 1996 video game set in Peru, Greece, Egypt, and Atlantis |
| 32% | TEMPLERUN | 9 | Video game franchise with evil chaser monkeys |
| 32% | DRAGONQUEST | 11 | Video game franchise with fire-breathing creatures |
| 32% | MYST | 4 | Video game franchise with the main character Atrus |
| 32% | THESIMS | 7 | Video game franchise with the cheat code "rosebud" |
| 32% | SILENTHILL | 10 | Sean Bean/Laurie Holden horror film based on a video game franchise set in a monster-filled town (2 wds.) |
| 31% | HALO | 4 | Sci-fi video game franchise with militaristic aliens |
| 31% | JENNIFER | 8 | With 35-Across, actress who starred in both the "Hunger Games" and "X-Men" movie franchises |
| 30% | ANGRYBIRDS | 10 | Video game franchise in which the enemies are pigs |
| 29% | CSI | 3 | Franchise with a ''Hard Evidence'' video game |
| 29% | SIM | 3 | Video game character in a virtual city |
| 29% | INJUSTICE | 9 | Video game set in alternate DC Comics universe |
| 29% | HALFLIFE | 8 | Video game set in a dimension called Xen |
| 29% | NCIS | 4 | Franchise with a series set in New Orleans |
| 29% | RPG | 3 | Video game genre with quests and adventures: Abbr. |