| 100% | THESIMS | 7 | Video game franchise with the cheat code "rosebud" |
| 64% | MYST | 4 | Video game franchise with the main character Atrus |
| 60% | THESIMS | 7 | Video game with a "rosebud" cheat code that grants free money |
| 58% | SEGA | 4 | Video game company with the Super Monkey Ball franchise |
| 58% | SEGA | 4 | Video game company with the "Virtua Fighter" franchise since 1993 |
| 57% | SEGA | 4 | Video game company with the After Burner and Virtua Fighter franchises |
| 57% | MARIOBROS | 9 | Video game franchise with characters found at the ends of 17-, 20-, 53- and 58-Across |
| 51% | TEMPLERUN | 9 | Video game franchise with evil chaser monkeys |
| 51% | DRAGONQUEST | 11 | Video game franchise with fire-breathing creatures |
| 49% | HALO | 4 | Sci-fi video game franchise with militaristic aliens |
| 48% | HALO | 4 | Video game franchise set in the 26th century |
| 48% | HALO | 4 | Video game series with the protagonist Master Chief |
| 48% | SEGA | 4 | Company with the Streets of Rage video game franchise |
| 47% | ANGRYBIRDS | 10 | Video game franchise in which the enemies are pigs |
| 47% | SUPERMARIO | 10 | Video game franchise set in the Mushroom Kingdom (2 wds.) |
| 47% | SEGA | 4 | Gaming company with the Yakuza franchise |
| 46% | CSI | 3 | Franchise with a ''Hard Evidence'' video game |
| 46% | AAA | 3 | Video game with the highest development budget |
| 45% | RAIDER | 6 | Video game with the character Lara Croft: Tomb __ |
| 45% | KONAMI | 6 | Video-game company with an eponymous cheat code |
| 45% | SEGA | 4 | Game company with the Virtua Fighter and Yakuza franchises |
| 44% | LARACROFT | 9 | Video game character with the most appearances on magazine covers, per Guinness (1,200+) |
| 44% | BEARS | 5 | N.F.L. franchise with the most overall games played (1,472) |
| 44% | UNDERTALE | 9 | 2015 indie video game with the song "Megalovania" |
| 44% | HALO | 4 | 2001 video game with the subtitle "Combat Evolved" |
| 43% | MADDENNFL | 9 | Video game franchise that featured 15-Across on the cover of the 2011 version: 2 wds. |
| 43% | RAINBOWSIX | 10 | Tom Clancy video game franchise about a counterterrorist unit with a colorful title: 2 wds. |
| 43% | SPLINTERCELL | 12 | Tom Clancy video game franchise about a black-ops subdivision within the NSA: 2 wds. |
| 42% | KONG | 4 | "Donkey ___," video game franchise featuring a giant gorilla that took over cereal boxes in the '80s |
| 42% | SEGA | 4 | Video game company that produced the Sonic the Hedgehog and Super Monkey Ball franchises |