| 100% | ROLLO | 5 | Viking who was the first ruler of Normandy |
| 96% | ROLLO | 5 | Norse Viking who was the first ruler of Normandy |
| 55% | INDIRA | 6 | Gandhi who was the first female PM of India |
| 54% | SEAN | 4 | Parker who was the first president of Facebook |
| 54% | PELOSI | 6 | Congresswoman Nancy who was the first female Speaker of the House |
| 54% | RICE | 4 | Condoleezza who was the first female African-American secretary of state |
| 54% | TOM | 3 | Landry who was the first coach of the Cowboys |
| 53% | DAVID | 5 | Letterman who was the first host of 15-Across |
| 53% | RIDGE | 5 | Tom who was the first Secretary of Homeland Security |
| 53% | BEV | 3 | Politician Perdue who was the first woman elected governor of North Carolina |
| 53% | MARSAIMARTIN | 12 | Producer who was the first cover star of Essence's Girls United |
| 53% | EMIL | 4 | Comedian Wakim who is the first Lebanese American cast member of "SNL" |
| 53% | TAMERLANE | 9 | First ruler of the Timurid Empire who died in 1405 |
| 53% | ALLEN | 5 | Steve who was the first host of "The Tonight Show" |
| 53% | MOHR | 4 | Jay who was the first host of "Last Comic Standing" |
| 53% | EVA | 3 | Perón who was the First Lady of Argentina |
| 53% | TYRA | 4 | Banks who was the first African-American woman on the cover of GQ |
| 53% | GERE | 4 | Richard who was the first man featured on the cover of American Vogue |
| 53% | OLGA | 4 | Korbut who was the first inductee to the International Gymnastics Hall of Fame |
| 53% | CANDICEBERGEN | 13 | Actress who was the first female host of "Saturday Night Live": 2 wds. |
| 53% | FAE | 3 | Baby who was the first infant subject of a xenotransplant procedure in 1984 |
| 52% | STENGEL | 7 | Casey who was the first manager of the New York Mets |
| 52% | REGIS | 5 | Philbin who was the first host of "America's Got Talent" |
| 52% | CHARLESKURALT | 13 | Journalist who was the first host of 48-Across (2 wds.) |
| 52% | MEL | 3 | Allen who was the first host of "This Week in Baseball" |
| 52% | CHEVYCHASE | 10 | Comedian who was the first host of 31-Across (2 wds.) |
| 52% | MARIECURIE | 10 | Scientist who was the first female professor at the University of Paris: 2 wds. |
| 52% | HAYES | 5 | Actress Helen who was the first person to win the Triple Crown of Acting |
| 52% | MIA | 3 | Hamm who was the first woman inducted into the World Football Hall of Fame |
| 52% | TYRA | 4 | Banks who was the first African-American woman featured on the cover of "GQ" |