| 100% | HIV | 3 | Virus that causes an acquired disease, that may be spread through intimate contact : Abbr. |
| 36% | CPR | 3 | Lifesaving procedure that might be performed by an EMT: Abbr. |
| 32% | NDA | 3 | Part of a severance contract that may be illegal, per an N.L.R.B. ruling: Abbr. |
| 31% | MAYO | 4 | Spread that may be "held" |
| 31% | POX | 3 | Disease that might be of the "chicken" or "small" variety |
| 31% | EXES | 4 | People that might be deleted from your contacts |
| 31% | NEUTRINOS | 9 | Particles that may be created through beta decay |
| 30% | ASAP | 4 | Abbr. that might be next to [IMPT] |
| 30% | DAK | 3 | State that may be north or south, abbr. |
| 30% | ACS | 3 | Coolers that may be on window sills: Abbr. |
| 30% | PTSD | 4 | Condition that may be treated with psilocybin: Abbr. |
| 30% | PBJ | 3 | Sandwich that might be made with Jif: Abbr. |
| 30% | UFOS | 4 | Ships that might be piloted by Martians: Abbr. |
| 30% | PBJ | 3 | Sandwich that might be made with Skippy: Abbr. |
| 30% | PATHOGEN | 8 | Bacteria or virus that causes disease |
| 30% | CUSTARD | 7 | Pie that may be an eyeful? |
| 30% | SSNS | 4 | Info that may be phished: Abbr. |
| 30% | RTE | 3 | Thoroughfare that may be "scenic": Abbr. |
| 30% | IPA | 3 | Brew that may be hazy: Abbr. |
| 30% | IRAS | 4 | Accounts that may be "traditional": Abbr. |
| 30% | ANTS | 4 | Insects that might be an "army" |
| 29% | DNA | 3 | Genetic substance that may be entered into evidence: Abbr. |
| 29% | ETD | 3 | Something that may be delayed by a storm: Abbr. |
| 29% | OBJ | 3 | Grammatical element that may be direct or indirect: Abbr. |
| 29% | FOMO | 4 | Anxiety that may be worsened by social media: abbr. |
| 29% | TSP | 3 | Amount that might be "heaping" in a recipe: Abbr. |
| 29% | UFO | 3 | Mysterious aircraft that might be piloted by aliens: Abbr. |
| 29% | MRI | 3 | Medical test that might be rough for claustrophobics: Abbr. |
| 29% | DUI | 3 | Crime that might be proven with a breathalyzer: Abbr. |
| 29% | OJS | 3 | Drinks that might be labeled as "pulp-free": Abbr. |