| 100% | SERVE | 5 | Wait to play the first shot |
| 73% | SERVE | 5 | Wait to play first shot |
| 63% | SERVING | 7 | Playing the first shot in tennis |
| 56% | EDITORS | 7 | The first people to play crosswords |
| 53% | DEE | 3 | Sandra who was the first to play "Gidget" |
| 52% | ERICBANA | 8 | First person to play the Hulk in the 2000s |
| 52% | NIMOY | 5 | Actor Leonard who was the first to play Spock |
| 52% | DEE | 3 | Actress Sandra who was the first to play Gidget |
| 52% | DEE | 3 | Actress Sandra who was the first to play "Gidget" |
| 52% | ALYN | 4 | Kirk ___, actor who was the first to play Superman |
| 52% | ALEC | 4 | Baldwin who was the first to play Jack Ryan |
| 52% | ICE | 3 | ___ hockey, Winter Olympic sport in which two teams use sticks to shoot a rubber puck and was first played in the 19th century |
| 52% | IRA | 3 | Aldridge who was the first Black actor to play Othello |
| 52% | PAWN | 4 | Chess piece that's often the first to be played |
| 51% | REBA | 4 | Singer McEntire who was the first woman to play Colonel Sanders |
| 51% | ALEC | 4 | Actor Guinness who was the first to play Obi-Wan Kenobi |
| 51% | LORRE | 5 | Peter who was the first actor to play a Bond villain |
| 51% | JAWS | 4 | First major film to be shot on the ocean |
| 50% | TOBEY | 5 | Actor Maguire who was the first to play Spider-Man in movies |
| 50% | RADIO | 5 | It was used to play music for the first time in 1906 |
| 49% | NAT | 3 | ___ "Sweetwater" Clifton, one of the first Black players to play in the NBA |
| 49% | ALYN | 4 | Kirk ___, the first actor to play Superman in live-action for the 1948 movie |
| 49% | SIT | 3 | Wait to play |
| 48% | LEBRON | 6 | Father in the first father-son pair to play in the same 36 Down game |
| 48% | BENNYGOODMAN | 12 | Big Band bandleader who was the first jazz bandleader to play Carnegie Hall (2 wds.) |
| 48% | ANDREAMCARDLE | 13 | Tony-nominated actress who was the first to play 40-Across on Broadway (2 wds.) |
| 48% | LEAD | 4 | Play the first card |
| 48% | LED | 3 | Played the first card |
| 48% | CLEAR | 5 | Badminton shot played to the back of the opponent's court |
| 47% | JACOBY | 6 | Ellsbury who was the first Native American of Navajo descent to play in Major League Baseball |