| 100% | IPOD | 4 | Walkman's 21st-century analog |
| 51% | DORA | 4 | 21st century explorer |
| 50% | LASERMOUSE | 10 | 21st century gaming accessory |
| 50% | LORDE | 5 | "The 21st century's author of adolescent evolution," per Cyrena Touros |
| 48% | IMS | 3 | Contacts 21st century-style |
| 47% | UPDATE | 6 | Bring into the 21st century |
| 47% | MMI | 3 | Start of the 21st century |
| 46% | BIDEN | 5 | 21st-century U.S. president |
| 46% | TRUMP | 5 | 21st-century U.S. president |
| 46% | OBAMA | 5 | 21st-century U.S. president |
| 46% | JOEBIDEN | 8 | 21st-century U.S. president |
| 45% | DOTCOMEXPLOSION | 15 | Boom of the early 21st century |
| 45% | OBAMACRAT | 9 | Certain liberal of the 21st century |
| 43% | CIRQUE | 6 | __ du soleil, traveling show for the 21st century |
| 42% | NOAH | 4 | "21 Lessons for the 21st Century" author Yuval ___ Harari |
| 42% | ADELE | 5 | Singer with the bestselling album of the 21st century |
| 42% | ALPHA | 5 | Generation ___, first to be born in the 21st century |
| 42% | TIMOR | 5 | __-Leste: first new sovereign state of the 21st century |
| 41% | DATASCIENTIST | 13 | "Sexiest job of the 21st century," per Harvard Business Review |
| 41% | BROKEBACKMOUNTAIN | 17 | Couple in the 21st century with Best Director Oscar winners |
| 40% | NEW | 3 | 21st-century |
| 39% | SAMUELALITO | 11 | Second Supreme Court justice confirmed in the 21st century (2006): 2 wds. |
| 39% | SONIASOTOMAYOR | 14 | Third Supreme Court justice confirmed in the 21st century (2009): 2 wds. |
| 39% | JOHNROBERTS | 11 | First Supreme Court justice confirmed in the 21st century (2005): 2 wds. |
| 39% | RAVENSYMONE | 11 | Actress in "The Cheetah Girls" and "Zenon: Girl of the 21st Century" |
| 39% | MML | 3 | 21st-century year |
| 39% | EURO | 4 | 21st-century currency |
| 39% | BIDEN | 5 | 21st-century president |
| 39% | OBAMA | 5 | 21st-century president |
| 39% | WIFI | 4 | 21st-century "necessity" |