| 100% | NAE | 3 | Washington-based org. that represents over 45,000 US churches |
| 31% | DAR | 3 | Org. that studies U.S. history |
| 31% | IOOF | 4 | Benevolent org. with over 10,000 US lodges |
| 30% | NEA | 3 | Labor org. that represents teachers |
| 30% | CIA | 3 | US org. that gathers foreign intelligence |
| 29% | STAR | 4 | Symbol that represents a state on the US flag |
| 29% | KGB | 3 | Org. that "Moscow Centre" represents in George Smiley novels |
| 29% | ILA | 3 | Big org. that represents many NY dockworkers |
| 29% | CMA | 3 | Org. that has given Reba McEntire over 50 award nominations |
| 29% | WWE | 3 | Org. that merged with the U.F.C. in 2023 |
| 29% | SPOKANE | 7 | US city in Washington that hosted Expo '74 |
| 29% | ANS | 3 | US org. that has promoted onomastics since 1951 |
| 28% | NFC | 3 | Org. that a 22-Across will represent during Super Bowl LVIII |
| 28% | AFC | 3 | Org. that a 9-Across will represent in Super Bowl LVIII |
| 28% | RSA | 3 | US org. that researches the ancient art of persuasion (abbr.) |
| 28% | SPOKANE | 7 | City in Washington, US, that hosted Expo '74 |
| 27% | AHUA | 4 | Nonprofit DC-based advocacy org. since 1932 that strives to represent the interests of the motoring public |
| 27% | FDA | 3 | Org. that caused Endo International to remove Opana ER from the US market |
| 27% | FEMA | 4 | U.S. org. that helps local governments respond to disasters |
| 27% | DELAWARE | 8 | State that 16-Across represented in the US Senate |
| 27% | DELAWARE | 8 | State that Joe Biden represented as a US senator |
| 27% | ACC | 3 | Sports org. that now includes U.C. Berkeley and Stanford, strangely enough |
| 26% | ILL | 3 | State that Barack Obama represented in the US Senate: Abbr. |
| 26% | ASPCA | 5 | Humane org. that's over 150 years old |
| 26% | AARP | 4 | U.S. org. with over 39 million members |
| 26% | OED | 3 | Ref. work with over 45,000 obsolete words |
| 26% | SEATTLE | 7 | City in Washington, US, that hosted the 1962 World's Fair |
| 26% | IEN | 3 | Org. that has represented Native American concerns to the UN and has a Carbon Pricing Toolkit |
| 25% | AHS | 3 | Org. based at Alexandria's River Farm that awards the Great American Gardeners Awards |
| 25% | SPOKANE | 7 | City in Washington, US, that hosted the Expo '74 world's fair |