| 100% | ROSIETHERIVER | 13 | Waterway named for a talk show host? |
| 81% | OWN | 3 | Cable channel named for a talk show host |
| 70% | DESK | 4 | Furniture piece for a talk show host |
| 66% | LAPELMIC | 8 | Bit of gear for a talk show host |
| 60% | RICKILAKE | 9 | Former talk show host with a "watery" name: 2 wds. |
| 57% | MARIEOSMOND | 11 | Singer and talk show host who has been a spokesperson for Nutrisystem: 2 wds. |
| 57% | JIMMYKIMMEL | 11 | Talk show host who recently hosted the Oscars for the second year in a row: 2 wds. |
| 56% | ELLENDEGENERES | 14 | Talk show host and star of a 1990s ABC sitcom, whose title was her first name: 2 wds. |
| 52% | DESK | 4 | What a talk show host usually sits behind |
| 52% | JOANRIVERS | 10 | Late comedian/talk show host with a "watery" name: 2 wds. |
| 51% | CONAN | 5 | Talk show hosted by a Harvard grad |
| 51% | CHARLIEROSE | 11 | Talk show host named in the #MeToo movement |
| 51% | OPRAH | 5 | Talk show host nominated for an Academy Award |
| 51% | DROZ | 4 | Talk show host whose first name is Mehmet |
| 50% | LATE | 4 | "___ Night" (2019 film starring Emma Thompson as a talk show host) |
| 50% | ELLEN | 5 | Talk show host known for dancing in the audience |
| 50% | ARSENIOHALL | 11 | Talk show host who won a season of "Celebrity Apprentice" |
| 49% | LETTERMAN | 9 | David __, US TV talk show host for 33 years |
| 49% | CONANOBRIEN | 11 | Longtime talk show host with a degree from Harvard |
| 49% | PHIL | 4 | "Dr. ___" (American talk show hosted by a clinical psychologist) |
| 48% | GEORGELOPEZ | 11 | Talk show host who plays a teacher in "Spare Parts": 2 wds. |
| 48% | ELLENDEGENERES | 14 | Daytime talk show host who is a vegan: 2 wds. |
| 48% | EMMY | 4 | Trophy for a game show host, for example |
| 48% | LOOK | 4 | "Don't ___ Up," Oscar-nominated 2021 film featuring Tyler Perry as a talk show host |
| 48% | ELLEN | 5 | Longtime talk show host known for pulling pranks on her guests |
| 47% | OPRAH | 5 | Talk show queen named after a figure in Ruth |
| 47% | OPENLINE | 8 | Opportunity for a radio talk show caller |
| 47% | PHONEIN | 7 | Call a talk-show host |
| 46% | CHANDLERBING | 12 | Cherry for talk show host Chelsea? |
| 46% | THEOC | 5 | TV show named for a county |