| 100% | MEAT | 4 | What tempeh can be a substitute for |
| 82% | MEAT | 4 | What seitan can be a substitute for |
| 55% | ACTSAS | 6 | Is a substitute for |
| 54% | YEN | 3 | What can be bought by the dozen for about a dime |
| 49% | SPIGOT | 6 | What can be a turnoff? |
| 49% | PLEA | 4 | What could be a bargain |
| 49% | IDS | 3 | What irises can be used for |
| 49% | TOKE | 4 | What can be a real drag? |
| 48% | PRON | 4 | Part of the speech that is a substitute for a noun, for short |
| 48% | CUD | 3 | What can be a lot to stomach? |
| 48% | PARTS | 5 | What a junker may be good for |
| 48% | ORGAN | 5 | What a fugue may be written for |
| 48% | LIBEL | 5 | What a tabloid may be sued for |
| 48% | COMEDIEDIEFFECT | 15 | What a pratfall may be done for |
| 48% | ORE | 3 | What a prospector may be searching for |
| 48% | LIBEL | 5 | What a newspaper might be sued for |
| 48% | BOOTH | 5 | What a host may be asked for |
| 48% | TEESHOT | 7 | What a driver might be employed for |
| 48% | MED | 3 | What a script might be written for |
| 48% | ALLAGES | 7 | What a family film is appropriate for |
| 48% | FASTSTART | 9 | What a pace horse is noted for |
| 48% | ORE | 3 | What a gold digger is looking for |
| 48% | AREA | 4 | What many a rug is made for |
| 48% | RANGE | 5 | What a versatile actor is praised for |
| 47% | EDAM | 4 | It can be substituted for Gouda |
| 47% | STOODIN | 7 | Was a substitute (for): 2 wds. |
| 47% | WATERBREAK | 10 | Time for a drink at the gym... or what can literally be seen in 17-, 24-, 35- and 49-Across |
| 47% | CASELOAD | 8 | Can be heavy for a cop or social worker |
| 47% | AGAVE | 5 | Syrup that can be substituted for honey |
| 46% | CONTACT | 7 | __ lenses are a good substitute for glasses |