| 100% | WIL | 3 | Wheaton who has appeared as himself on "The Big Bang Theory" |
| 68% | WIL | 3 | Wheaton who plays himself on The Big Bang Theory |
| 63% | WIL | 3 | Actor Wheaton who had a recurring role on "The Big Bang Theory" |
| 63% | WIL | 3 | Wheaton who played himself on "The Big Bang Theory" |
| 60% | WILWHEATON | 10 | "Star Trek: The Next Generation" actor who guest stars as himself on "The Big Bang Theory" (2 wds.) |
| 57% | WIL | 3 | Actor Wheaton who has guest appearances on "The Big Bang Theory" |
| 52% | WIL | 3 | Actor Wheaton who made several guest appearances on "The Big Bang Theory" |
| 49% | DEAN | 4 | "Breaking Bad" actor Norris who had a recurring role on "The Big Bang Theory" |
| 48% | PARSONS | 7 | Jim who plays Sheldon on The Big Bang Theory |
| 48% | WIL | 3 | Actor Wheaton who occasionally guest-stars on "The Big Bang Theory" |
| 48% | WIL | 3 | Actor Wheaton who's guest-starred on "The Big Bang Theory" |
| 48% | WIL | 3 | Wheaton who starred in The Big Bang Theory |
| 47% | WIL | 3 | "Star Trek: TNG" actor Wheaton who made several guest appearances on "The Big Bang Theory" |
| 46% | TAKEI | 5 | "Star Trek" actor George who has had cameos on "The Big Bang Theory" and "King of the Nerds" |
| 46% | HAWKING | 7 | Physicist Stephen, guested on The Big Bang Theory |
| 45% | RAJ | 3 | Kunal Nayyar's character on The Big Bang Theory |
| 44% | WIL | 3 | Wheaton with guest appearances on "The Big Bang Theory" |
| 44% | AMY | 3 | ___ Farrah Fowler, neuroscientist from "The Big Bang Theory" who has a Ph.D. in Neurobiology |
| 43% | RAJ | 3 | One of five characters on "The Big Bang Theory" to appear in every episode |
| 43% | CUOCO | 5 | Kaley who played Penny on "The Big Bang Theory" |
| 42% | JIMPARSONS | 10 | Actor who plays Sheldon on "The Big Bang Theory" (2 wds.) |
| 42% | JOHNNYGALECKI | 13 | Actor who plays Leonard on "The Big Bang Theory" (2 wds.) |
| 42% | KALEYCUOCO | 10 | Actress who plays Penny on "The Big Bang Theory" (2 wds.) |
| 42% | AOC | 3 | Rep. who has appeared as a guest judge on “RuPaul’s Drag Race” |
| 42% | MAYIM | 5 | ___ Bialik, Emmy-nominated actress best known for her role in "The Big Bang Theory" who has a degree in Neuroscience |
| 42% | BOB | 3 | Newhart who played Professor Proton on "The Big Bang Theory" |
| 42% | MELISSA | 7 | Actress Rauch who played Bernadette on "The Big Bang Theory" |
| 41% | WIL | 3 | Actor Wheaton with a recurring role on "The Big Bang Theory" |
| 41% | JUDDHIRSCH | 10 | "Superior Donuts" actor who guest stars as Leonard's dad on "The Big Bang Theory" (2 wds.) |
| 41% | LAURIEMETCALF | 13 | "Lady Bird" actress who guest stars as Sheldon's mom on "The Big Bang Theory" (2 wds.) |