| 100% | ATSIX | 5 | When one hand's up and the other's down |
| 87% | ATSIX | 5 | When a hand's up and the other's down |
| 50% | SIXAM | 5 | When hands are extended straight up and down |
| 50% | SIGNS | 5 | Touches one's chin and moves the hand down to say "Thank you," for example |
| 46% | SEESAWED | 8 | Had one's ups and downs |
| 46% | SEESAWED | 8 | Had one's ups and downs? |
| 45% | BOTH | 4 | One and the other |
| 45% | NODS | 4 | Moves one's head up and down in agreement |
| 45% | NODS | 4 | Moves one’s head up and down |
| 44% | BOTH | 4 | The one and the other |
| 44% | OVERBITE | 8 | When one's upper jaw is farther out than the lower |
| 44% | FAD | 3 | It's in one year and out the other |
| 44% | FAD | 3 | It's in one era and out the other |
| 43% | YOYO | 4 | Go up and down, like one's weight: Hyph. |
| 43% | PHILTRUM | 8 | The groove between one's nose and upper lip |
| 42% | SWEAR | 5 | What one may do up and down |
| 42% | BOTH | 4 | This one and the other one, too |
| 42% | CHILLEDWITHFEAR | 15 | "... and when I hand-deliver a package, the recipients are positively ___ - it's very satisfying!" |
| 42% | HEADTOTOE | 9 | Up and down the body |
| 42% | CUESTA | 6 | Hill that's steep on one side and gentle on the other |
| 42% | ASL | 3 | Syst. in which "Deaf Power" can be indicated by an open palm over one ear and the other hand forming a closed fist in the air |
| 41% | SEESAW | 6 | The ups and downs of childhood? |
| 41% | ASL | 3 | Syst. in which bobbing one’s fist up and down translates to “yes” |
| 41% | DISC | 4 | It's black on one side and white on the other, in Othello |
| 41% | AWOKE | 5 | Slammed one's hand down on the alarm, say |
| 41% | YOYODIETER | 10 | One whose weight goes up and down |
| 41% | MOUNTAINBIKER | 13 | One going through cyclic ups and downs? |
| 40% | QUIDPROQUO | 10 | One hand washing the other, so to speak |
| 40% | YAXIS | 5 | One going up and down in a plane? |
| 40% | SEESAW | 6 | Up and down we go in the park |