| 100% | MRS | 3 | Wife, once, with "the" |
| 81% | HEP | 3 | With the time, once |
| 75% | OTOE | 4 | Tribe allied with the Missouri, once |
| 71% | BORAT | 5 | Sacha Baron Cohen character with the catchphrase "My wife!" |
| 70% | ALI | 3 | Comedian Wong with the 2018 Netflix special "Hard Knock Wife" |
| 70% | ELLE | 4 | Singer King with the 2023 album "Come Get Your Wife" |
| 68% | TWICE | 5 | Cite problem with wife more than once |
| 67% | KAY | 3 | Mary ___ cosmetics, that shares its name with the Wife from "The Godfather" |
| 65% | ORIENT | 6 | Mysterious locale, once, with "the" |
| 65% | MRS | 3 | Wife, with "the" |
| 64% | LORAX | 5 | "The ___" (Dr. Seuss book with truffula trees and the Once-ler |
| 64% | PEG | 3 | Al Bundy's wife on the sitcom "Married... With Children" |
| 64% | TRIBORO | 7 | The Big Apple's RFK Bridge, once, with "the" |
| 63% | ORIENT | 6 | China and environs, once, with "the" |
| 63% | SYR | 3 | Country once joined with Egypt as the United Arab Republic: Abbr. |
| 62% | CARLOS | 6 | With 76-Across, Mexican business magnate who was once the world's richest person |
| 62% | FERNDALE | 8 | Detroit suburb named for the plants the area was once overgrown with |
| 62% | JAYZ | 4 | Rapper who put out the album "Everything Is Love" with wife Beyoncé |
| 61% | WONDERBRAS | 10 | Products once advertised with the slogan "Hello boys" |
| 61% | ZIMA | 4 | Drink once marketed with the tagline "Zomething different" |
| 61% | MICHELLE | 8 | With 27-Down, actress who plays the wife of 15-Across in "The Greatest Showman" |
| 60% | MARGARETBUNDY | 13 | The wife of Al Bundy on "Married... with Children," portrayed by Katey Sagal: 2 wds. |
| 60% | ARAL | 4 | With 45-Across, what was once the world's fourth-largest inland body of water |
| 60% | JOE | 3 | Actor Manganiello who filmed the upcoming drama "Stano" with his wife, Sofia Vergara |
| 60% | KEDS | 4 | Product once touted with the slogan "They feel good" |
| 59% | OZZIENELSON | 11 | He played himself as the dad on his show with wife Harriet: 2 wds. |
| 59% | ROMO | 4 | Former Dallas QB Tony whose third son with wife Candice is on the way |
| 58% | SOTHAT | 6 | With the result |
| 58% | DOWNSTREAM | 10 | With the current |
| 58% | SOAS | 4 | With the intent |