| 100% | DERMAL | 6 | With 12-Down, lidocaine delivery option |
| 58% | TALL | 4 | With 12 Down, unlikely story |
| 56% | SAYS | 4 | With 12-Down, turns down |
| 53% | THESTIFLE | 9 | With 12 Down, nickname for French NBA defensive star Rudy Gobert |
| 51% | MIDNIGHT | 8 | With 12 Down, spooky Netflix series about a church on a remote island |
| 49% | PINCE | 5 | With 12-Down, eyeglasses |
| 49% | ILL | 3 | With 12-Down, unfit |
| 48% | RUE | 3 | With 12-Down, buttercup relatives |
| 48% | SAINT | 5 | With 12-Down, fiery guy? |
| 48% | MAN | 3 | With 12-Down, not natural |
| 48% | FIREPLACE | 9 | With 12-Down, poker target |
| 48% | ITS | 3 | With 12-Down, "Gimme that!" |
| 47% | CLUE | 4 | With 12-Down, secretly plots (with) |
| 47% | MALL | 4 | With 12-Down, a modern idler |
| 47% | CAT | 3 | With 12-Down, a hospital procedure |
| 47% | RAP | 3 | With 12-Down, they show convictions |
| 47% | ACONNECTICUTYANKEE | 18 | With 12-Down, 1889 Twain novel |
| 47% | OSOLE | 5 | With 12-Down, classic Neapolitan tune |
| 47% | ISAAC | 5 | With 12-Down, Carnegie Hall icon |
| 47% | NEW | 3 | With 12-Down, Zooey Deschanel sitcom |
| 47% | AUDIO | 5 | With 12-Down, live-broadcast elements |
| 46% | SAN | 3 | With 12-Down, where the fault lies? |
| 46% | TERI | 4 | With 12-Down, a "Tootsie" co-star |
| 46% | HAIRS | 5 | With 12-Down, rifle shooter's aid |
| 46% | WES | 3 | With 12-Down, "Isle of Dogs" director |
| 46% | NOPAIN | 6 | With 12-Down, mantra on embracing difficulty |
| 46% | LIP | 3 | With 12-Down, type of cosmetic pencil |
| 46% | HOLLYWOOD | 9 | With 12-Down, locale of the 4-Down |
| 46% | ALLI | 4 | With 12-Down, start of a simple request |
| 46% | TIN | 3 | With 12-Down, source of metal for cans |