| 100% | ITENDS | 6 | With 13-Across, 2024 movie based on a Colleen Hoover novel |
| 59% | ITENDSWITHUS | 12 | 2024 box-office hit based on a Colleen Hoover novel ... whose title is a "spoiler" for 20-, 28-, 39-, and 47-Across |
| 46% | EYRE | 4 | "Jane ___" (2011 movie based on a classic novel) |
| 46% | VENDETTA | 8 | "V for ___" (2005 dystopian action movie based on a graphic novel) |
| 45% | SHOPGIRL | 8 | 2005 Steve Martin movie based on a novel he wrote |
| 44% | ARGYLLE | 7 | 2024 movie based on a book by Elly Conway (which some claim is a pseudonym for Taylor Swift) |
| 44% | WARHORSE | 8 | 2011 movie based on a Michael Morpurgo novel |
| 44% | FORRESTGUMP | 11 | 1994 movie based on a Winston Groom novel |
| 44% | MISERY | 6 | 1990 movie based on a Stephen King novel |
| 44% | EMMA | 4 | 2020 movie based on a Jane Austen novel |
| 43% | WIZ | 3 | 1974 musical based on a 1900 novel, with "The" |
| 43% | FORREST | 7 | "___ Gump," Tom Hanks movie based on a novel by Winston Groom which released in 1994 |
| 42% | MOTHERNIGHT | 11 | Nick Nolte movie based on a Kurt Vonnegut novel |
| 41% | FATHER | 6 | Play based on a Clarence Day novel: Life With __ |
| 41% | STARS | 5 | "The Fault in Our ___" (2014 movie based on a young-adult novel) |
| 41% | SEMATARY | 8 | Pet __, 2019 movie based on a Stephen King novel |
| 40% | CHARLOTTESWEB | 13 | 2006 Julia Roberts kids' movie, based on an E.B. White novel, whose title begins with a woman's name: 2 wds. |
| 40% | THETHORNBIRDS | 13 | 1983 miniseries based on a Colleen McCullough novel, starring Richard Chamberlain and Rachel Ward: 3 wds. |
| 40% | DUNE | 4 | 1984 sci-fi movie based on a Frank Herbert novel |
| 40% | BFG | 3 | 2016 film based on a Roald Dahl novel, with "The" |
| 40% | MEANGIRLS | 9 | 2018 Broadway musical, based on a 2004 teen comedy, readapted into a 2024 movie musical: 2 wds. |
| 40% | CLUE | 4 | Movie based on a board game |
| 39% | PERSUASION | 10 | 2022 Netflix movie based on 18-Across's last completed novel |
| 39% | FILMADAPTATION | 14 | Movie based on a book or video game |
| 38% | HIGH | 4 | "___ Fidelity" (John Cusack movie based on a Nick Hornby novel) |
| 38% | HEIDI | 5 | TV movie, based on a Swiss children’s novel, that notoriously cut off a 1968 Jets-Raiders broadcast |
| 38% | CLUE | 4 | 1985 movie based on a board game |
| 38% | ANNIE | 5 | 2014 movie based on a Broadway musical |
| 38% | LES | 3 | "___ Misérables" (2012 movie based on a musical) |
| 38% | LESMIZ | 6 | 2012 movie musical based on a Victor Hugo novel, familiarly: 2 wds. |