| 100% | JOSEPH | 6 | With 14- and 45-Across, "Inception" actor who stars in 49-Across |
| 70% | NICHOLAS | 8 | With 37-Across, actor who stars in 49-Across as Neil Melendez and in "Being Mary Jane" as Orlando Lagos |
| 58% | KEVINHART | 9 | "Ride Along" actor/comedian who co-stars with Tiffany Haddish and 45-Across in 29-Across (2 wds.) |
| 56% | JENNIFER | 8 | With 45-Across, "Silver Linings Playbook" Oscar winner who stars in 21-Across and 37-Across |
| 55% | RICHARDBURTON | 13 | "Where Eagles Dare" actor who starred with Rod Steiger in "Breakthrough" and in 31-Across (2 wds.) |
| 55% | SETHMACFARLANE | 14 | Actor who starred in and made his directorial debut with 2012's "Ted": 2 wds. |
| 54% | PETER | 5 | With 7-Across, late actor who starred in "Easy Rider" |
| 54% | ROBERTMITCHUM | 13 | "The Winds of War" actor who starred with John Wayne in "El Dorado" and in 31-Across (2 wds.) |
| 54% | DENZEL | 6 | With 26-Across, "Malcolm X" actor who stars in 40-Across |
| 54% | BRADLEYCOOPER | 13 | Actor who starred in and made his directorial debut with 2018's "A Star Is Born": 2 wds. |
| 54% | BRUCEWILLIS | 11 | "A Good Day to Die Hard" actor who stars in 49-Across: 2 wds. |
| 53% | GEORGECLOONEY | 13 | Actor who starred in and made his directorial debut with 2002's "Confessions of a Dangerous Mind": 2 wds. |
| 52% | MACAULAYCULKIN | 14 | Child actor who starred in 19-Across and 47-Across: 2 wds. |
| 51% | RYANGOSLING | 11 | "Barbie" actor who stars in 15-Across, 35-Across, and 43-Across (2 wds.) |
| 51% | NEIL | 4 | With 15-Across, "How I Met Your Mother" actor who won a 2014 Tony Award for starring in "Hedwig and the Angry Inch" |
| 51% | STILLER | 7 | Actor Ben who stars in and directed 15-/47-Across |
| 51% | JASONSTATHAM | 12 | "Lock, Stock and Two Smoking Barrels" actor who stars in 16-Across and 51-Across (2 wds.) |
| 51% | JOHN | 4 | With 39-Across, "Snowpiercer" actor who starred as John Merrick in 16-Across |
| 50% | ANTONIATHOMAS | 13 | Actress who stars in 49-Across as Claire Browne and in "Lovesick" as Evie (2 wds.) |
| 50% | RALPHFIENNES | 12 | Actor who co-stars with 38-Across and Bill Murray in "The Grand Budapest Hotel" (2 wds.) |
| 50% | ROBERTDUVALL | 12 | "The Godfather" actor who starred in the 1989 miniseries based on 14-Across: 2 wds. |
| 50% | THURGOOD | 8 | With 56-Across, lawyer who argued in 19- and 49-Across |
| 49% | VALKILMER | 9 | Actor who starred in Top Gun and The Doors |
| 49% | JENNIFER | 8 | With 35-Across, actress who starred in both the "Hunger Games" and "X-Men" movie franchises |
| 49% | PITT | 4 | Actor Brad who costarred in "Mr. and Mrs. Smith" with 31-Across |
| 49% | MCQUEEN | 7 | Steve, actor who starred in Bullitt and Papillon |
| 49% | RYANGOSLING | 11 | Actor born November 12, 1980, who stars in 15-Across, 35-Across, and 43-Across (2 wds.) |
| 49% | NICOLE | 6 | With 34-Across, actress who starred in two miniseries based on "Nine Perfect Strangers" and 47-Across |
| 48% | GEORGECLOONEY | 13 | Actor who co-stars with 38-Across in "Michael Clayton" and with Bill Murray in "The Monuments Men" (2 wds.) |
| 48% | STREISAND | 9 | Barbra, singer and actor who starred in Funny Girl |