| 100% | STAN | 4 | With 2-Down, cocreator of Spider-Man |
| 76% | STANLEE | 7 | Cocreator of Iron Man and Spider-Man: 2 wds. |
| 69% | STANLEE | 7 | Cocreator of the Hulk and Spider-Man: 2 wds. |
| 67% | DOG | 3 | With 2 Down, bookmark of a sort |
| 57% | RAN | 3 | With 2-Down, was out of control |
| 56% | SAN | 3 | With 2-Down, seat of Costilla County, Colo. |
| 56% | ERIC | 4 | With 2-Down, star of 2003's "Hulk" |
| 56% | DOT | 3 | With 2-Down, end of the Gettysburg address? |
| 56% | PLUS | 4 | With 2-Down, symbol indicating a margin of error |
| 56% | MARYJANE | 8 | Romantic interest of Spider-Man: 2 wds. |
| 54% | PAPA | 4 | With 2 Down, parents |
| 54% | TOW | 3 | With 2-Down, type of zone in which parking is restricted |
| 53% | PORES | 5 | With 2 Down, studies closely |
| 53% | LAKE | 4 | With 2 Down, water bordering Cleveland |
| 52% | ROLL | 4 | With 2-Down, the name of one of Led Zeppelin's greatest hits, "___ & ___" |
| 52% | STANLEE | 7 | Cocreator of the Fantastic Four and the X-Men: 2 wds. |
| 52% | ONEA | 4 | With 59-Down, brand of multivitamins: 2 wds. |
| 52% | CAL | 3 | With 14-Down, "Iron Man" of sports |
| 52% | BEND | 4 | With 2-Down, stoop down |
| 52% | HOLY | 4 | With 2-Down, "Man alive!" |
| 52% | HUMAN | 5 | With 2-Down, it has roughly tripled in size since the time of australopithecines |
| 51% | STAN | 4 | With 130 Across, Spider-Man cocreator |
| 50% | BEER | 4 | With 1-Down, bit of litter in a man cave |
| 50% | ISWEAR | 6 | A promise not to, with 2 Down |
| 50% | GRAND | 5 | With 2-Down, U.S. national park that's larger than the entirety of Rhode Island |
| 49% | ANN | 3 | With 12-Down, founder of the American Shakers (born 2/29/1736) |
| 48% | THANTORECEIVE | 13 | With 2 Down, 36 Across & 43 Across, a Christmas-style maxim |
| 48% | PAULGIAMATTI | 12 | "Cinderella Man" and "Sideways" actor who turned down the role of Michael Scott on "The Office": 2 wds. |
| 48% | BILLIONAIRE | 11 | One with lots of 2-Down |
| 48% | LARRYTHE | 8 | With 28-Down, voice of Mater in the three "Cars" movies: 2 wds. |