| 100% | NCUTI | 5 | With 21-Down, “Doctor Who” and “Sex Education” star |
| 48% | DENTIST | 7 | Doctor who deals with tooth and gum issues |
| 46% | KEVIN | 5 | With 21-Across, NBA MVP and eight-time All-Star forward who plays for 44-Across/46-Across |
| 46% | OBGYN | 5 | Doctor who deals with pregnancies and women's health, for short: Hyph. |
| 43% | DAVIDTENNANT | 12 | 2005-2010 "Doctor Who" star whose first and last names each start and end with the same letter: 2 wds. |
| 42% | PESSIMIST | 9 | One who identifies with the answers to the starred Down clues |
| 42% | OMAR | 4 | With 21-Down, actor who portrayed Dr. Eric Foreman on "House" |
| 42% | ETS | 3 | Doctor Who and others, briefly |
| 42% | USER | 4 | With 21 Down, entrance requirements |
| 41% | DANA | 4 | With 21-Down, journalist who co-hosts CNN's "State of the Union" |
| 41% | JOSEPH | 6 | With 14- and 45-Across, "Inception" actor who stars in 49-Across |
| 40% | RONALD | 6 | With 39-Across, film star and future US president who was president of SAG, 1959-1960 |
| 40% | FAITHHILL | 9 | Country singer who stars with Tim McGraw and Sam Elliott on "1883" (2 wds.) |
| 40% | JOHNHURT | 8 | Starred in Alien and TV's Doctor Who and Merlin |
| 40% | LEE | 3 | With 25-Down, "Halt and Catch Fire" star |
| 40% | STATE | 5 | With 39 Across and 33 Down, what each syllable of the answer to each starred clue is |
| 40% | LADAINIAN | 9 | With 41-Across, running back who holds the single-season NFL touchdown record and wore number 21 |
| 40% | WRAP | 4 | With 61-Down, "Get a move on!" and an instruction for the answers to the starred clues |
| 40% | JENNIFER | 8 | With 45-Across, "Silver Linings Playbook" Oscar winner who stars in 21-Across and 37-Across |
| 39% | ARNAZ | 5 | Cuban-born Classic TV sitcom star who played Ricky Ricardo with his wife, 6 down |
| 39% | SETHMACFARLANE | 14 | Actor who starred in and made his directorial debut with 2012's "Ted": 2 wds. |
| 39% | TNIA | 4 | Miller of Bly Manor and Sex Education |
| 39% | JENNIFER | 8 | With 35-Across, actress who starred in both the "Hunger Games" and "X-Men" movie franchises |
| 39% | RANI | 4 | Doctor Who villainess, with "the" |
| 39% | RANI | 4 | Doctor Who villainess, with The |
| 39% | YOULL | 5 | With 21 Across, 3 Down, 8 Down, and 20 Down, response to Ralphie's request for a BB gun in "A Christmas Story" |
| 38% | ROUGH | 5 | With 21- and 25-Down, lacking refinement ... like this puzzle's grid? |
| 38% | VANILLA | 7 | With 27-Down, film starring Tom Cruise and Penélope Cruz |
| 38% | NYLE | 4 | ___ DiMarco, model and deaf activist who was the winner of season 22 of "Dancing With The Stars" |
| 38% | NICOLE | 6 | With 34-Across, actress who starred in two miniseries based on "Nine Perfect Strangers" and 47-Across |