| 100% | ROBERTSEAN | 10 | With 25-Across, actor who played Dr. James Wilson (based on 47-Across) on the Fox series "House": 2 wds. |
| 55% | TIMROTH | 7 | "Pulp Fiction" actor who played Dr. Cal Lightman on the Fox series "Lie To Me": 2 wds. |
| 48% | SPENCERTRACY | 12 | Actor who played the lawyer based on Clarence Darrow in 32-Across: 2 wds. |
| 47% | LUCYLIU | 7 | Actress who played Joan (based on 47-Across) on the CBS series "Elementary": 2 wds. |
| 46% | FREDRICMARCH | 12 | Actor who played the lawyer based on William Jennings Bryan in 32-Across: 2 wds. |
| 45% | MORRISCHESTNUT | 14 | Actor who plays the title character of 47-Across in a CBS series that premiered in January: 2 wds. |
| 45% | MARTINFREEMAN | 13 | "The Hobbit" actor who plays Dr. Watson on the BBC's "Sherlock": 2 wds. |
| 45% | MARTINFREEMAN | 13 | Actor who plays 22-Across/41-Across on the BBC series "Sherlock" (2 wds.) |
| 45% | LEONARD | 7 | Robert Sean ___, actor who plays Dr. James Wilson on "House, M.D." |
| 45% | SEANGIAMBRONE | 13 | Actor who plays the geeky boy, Adam, on 18-Across: 2 wds. |
| 44% | KYLECHANDLER | 12 | Actor who plays Cathcart in the Hulu miniseries based on 39-Across's "Catch-22" (2 wds.) |
| 44% | IANMCSHANE | 10 | The actor who plays Mr. Wednesday on the TV series "American Gods": 2 wds. |
| 44% | EMMADARCY | 9 | "Truth Seekers" actor who plays Rhaenyra Targaryen on the HBO series "House of the Dragon" (2 wds.) |
| 44% | HUGHLAURIE | 10 | British actor who played American Gregory House on Fox's "House": 2 wds. |
| 43% | KIERANCULKIN | 12 | "Igby Goes Down" actor who plays Logan Roy's son Roman on the HBO series "Succession": 2 wds. |
| 43% | MICHAELK | 8 | With 34-Across, "The Wire" actor who plays Bobby McCray on "When They See Us": 2 wds. |
| 43% | GEOFFREYRUSH | 12 | "Shine" actor who played Albert Einstein on the 2017 Nat Geo series "Genius": 2 wds. |
| 43% | JOHNMALKOVICH | 13 | "The New Pope" actor who plays Dr. Adrian Mallory on "Space Force": 2 wds. |
| 43% | WALTONGOGGINS | 13 | "Justified" actor who plays the main character Wade on 18-Across: 2 wds. |
| 43% | JACKALBERTSON | 13 | "Willy Wonka & the Chocolate Factory" actor who played "the Man" on the 1970s series "Chico and the Man": 2 wds. |
| 43% | EWANMCGREGOR | 12 | Actor who plays the protagonist in "Christopher Robin" which is a fantasy film based on "Winnie-the-Pooh": 2 wds. |
| 43% | GEORGECLOONEY | 13 | Actor/director who plays Scheisskopf in the Hulu miniseries based on 39-Across's "Catch-22" (2 wds.) |
| 42% | PETERUSTINOV | 12 | Actor who played Hercule Poirot in the 1978 film "Death on the Nile": 2 wds. |
| 42% | JIMMIEWALKER | 12 | Actor who played J.J. Evans, the character with the catchphrase "Dy-no-mite!" on the 1970s sitcom "Good Times": 2 wds. |
| 42% | KELSEYGRAMMER | 13 | Actor who played Dr. Frasier Crane on "Frasier": 2 wds. |
| 42% | MARKWILLIAMS | 12 | "Harry Potter" actor who plays the title crime-solving priest on the British TV series "Father Brown" (2 wds.) |
| 42% | JAMESBROLIN | 11 | "Marcus Welby, M.D." actor who plays the father on 29-/32-Across: 2 wds. |
| 42% | NICHOLASHOULT | 13 | Actor who plays the protagonist in "Jack the Giant Slayer," which is a fantasy film based on British fairy tales: 2 wds. |
| 41% | ROGERMOORE | 10 | Actor from the TV series "The Saint", who has played the role of James Bond in seven movies : 2 wds. |
| 41% | ALVAROMORTE | 11 | Actor who plays El Profesor on the Spanish-language Netflix drama series "Money Heist" (2 wds.) |