| 100% | SATURDAYNIGHT | 13 | With 25-Across, NBC sketch comedy series since 1975 whose regulars have included Gilda Radner, Eddie Murphy, and Tina Fey: 2 wds. |
| 31% | SNL | 3 | NBC sketch comedy series that has been airing since 1975: Abbr. |
| 25% | SNL | 3 | NBC show that gave Eddie Murphy and Tina Fey their start: Abbr. |
| 24% | ROCK | 4 | NBC comedy series starring Tina Fey and Alec Baldwin |
| 24% | MADTV | 5 | 1990s-2000s Fox sketch comedy series that introduced Alex Borstein, Jordan Peele, and Keegan-Michael Key: 2 wds. |
| 23% | DATENIGHT | 9 | 2010 comedy starring Steve Carell and Tina Fey: 2 wds. |
| 23% | SNL | 3 | Comedy series whose 12/21/19 host Eddie Murphy hadn't been on the show since 1984: Abbr. |
| 23% | WEEKENDUPDATE | 13 | Tina Fey's 9-Across segment with Jimmy Fallon: 2 wds. |
| 22% | AMYSCHUMER | 10 | Sketch comedy performer who wrote and stars in 41-Across: 2 wds. |
| 22% | SCTV | 4 | Sketch comedy series with Eugene Levy and Catherine O'Hara |
| 22% | SCTV | 4 | Sketch comedy series with Eugene Levy and Catherine O’Hara |
| 21% | SNL | 3 | Sketch comedy show on NBC since 1975: Abbr. |
| 21% | ROBERTSEAN | 10 | With 25-Across, actor who played Dr. James Wilson (based on 47-Across) on the Fox series "House": 2 wds. |
| 21% | MRSHOW | 6 | Sketch comedy series starring Bob Odenkirk and David Cross (and an anagram of 18 Across) |
| 20% | ROBOTCHICKEN | 12 | Stop-motion sketch comedy series on Adult Swim featuring a cyborg rooster: 2 wds. |
| 20% | COMEDYCENTRAL | 13 | Channel that airs 18-Across's self-titled sketch comedy series: 2 wds. |
| 20% | TRADINGPLACES | 13 | 1983 Eddie Murphy comedy that costarred Dan Aykroyd: 2 wds. |
| 20% | TRADINGPLACES | 13 | 1983 Eddie Murphy comedy directed by John Landis: 2 wds. |
| 20% | EMILYLITELLA | 12 | Gilda Radner's early "SNL" character with the catchphrase "Never mind": 2 wds. |
| 20% | INLIVING | 8 | "___ Color," '90s sketch comedy series created by Keenen Ivory Wayans which featured Jamie Foxx: 2 wds. |
| 20% | TINA | 4 | ___ Fey: best known for NBC sketch comedy series |
| 19% | MEANGIRLS | 9 | 2024 musical teen comedy written by Tina Fey starring 17-Across and 30-Across (2 wds.) |
| 19% | SATURDAYNIGHT | 13 | "____ Live," a sketch comedy show on NBC, which 40a hosted in 2016: 2 wds. |
| 19% | SNL | 3 | Longtime NBC sketch comedy series: Abbr. |
| 19% | MODERN | 6 | "___ Love," Amazon Prime Video romantic comedy series starring Tina Fey and Dev Patel among others |
| 19% | THEBIRTH | 8 | With 25-Across, 2016 film about a slave rebellion: 2 wds. |
| 19% | DOCUMENTARYNOW | 14 | IFC comedy series that spoofs films like "Grey Gardens" and "When We Were Kings": 2 wds. |
| 19% | MARIOKART | 9 | Nintendo racing game series whose drivers include Luigi and Peach: 2 wds. |
| 19% | INLIVINGCOLOR | 13 | 1990s Fox sketch comedy series, developed by Keenen Ivory Wayans, that gave Jamie Foxx and Jim Carrey their start: 3 wds. |
| 19% | WHENONECHANGES | 14 | With 25-, 44- and 50-Across, Murphy's traffic law |