| 100% | DESPERATE | 9 | With 26-Across, series on which Kyle MacLachlan portrayed Wisteria Lane resident Orson Hodge |
| 44% | PORTLANDIA | 10 | Series on which Kyle MacLachlan portrays the mayor of an Oregon city |
| 36% | TWINPEAKS | 9 | Series on which Kyle MacLachlan plays FBI Special Agent Dale Cooper: 2 wds. |
| 26% | DOOGIE | 6 | With 30-Across, physician portrayed by Neil Patrick Harris on a 1980s-1990s TV series |
| 25% | DIAGNOSISMURDER | 15 | Series on which Dick Van Dyke played a doctor who solves crimes with his detective son |
| 23% | GOODOMENS | 9 | Amazon series on which 31-Across plays the demon Crowley: 2 wds. |
| 23% | GAMEOFTHRONES | 13 | HBO fantasy series on which 18-Across played Lyanna Mormont: 3 wds. |
| 22% | THEGLEEPROJECT | 14 | Oxygen reality competition series on which 16- and 55-Across both appeared: 3 wds. |
| 21% | HANNIBAL | 8 | NBC drama on which 15-Across/9-Down portrayed Dr. Bedelia Du Maurier |
| 21% | LUKECAGE | 8 | Netflix superhero show on which 26-Across played a Harlem councilwoman: 2 wds. |
| 21% | RISHI | 5 | With 26 Across, Liz Truss's successor as British prime minister |
| 21% | GLEE | 4 | Fox series on which Lea Michele played Rachel Berry |
| 21% | CLONE | 5 | With 17-Across, series of conflicts with battles on Ryloth, Felucia, Malastare, and Kamino |
| 20% | BEL | 3 | With 39-Across, Peacock series based on a 1990s Will Smith show |
| 20% | DEN | 3 | "Dragons' ___" (international TV series on which "Shark Tank" is based) |
| 20% | ARCHER | 6 | FX spy series on which Aisha Tyler voices Lana Kane |
| 20% | JAI | 3 | With 26-Down, game played on a fronton |
| 20% | THEFALL | 7 | BBC drama on which 15-Across/9-Down portrays Detective Superintendent Stella Gibson: 2 wds. |
| 20% | MICHAEL | 7 | With 38-Across, "Lost" actor portraying billionaire Harold Finch on 14-/52-Across |
| 20% | SUPERBOWL | 9 | With 26 Across, memorable spots created by the answers to the starred clues |
| 20% | JESSICALANGE | 12 | She portrayed 14-Across on the FX series "Feud": 2 wds. |
| 20% | LILIES | 6 | "Water ___," a series of oil paintings by French impressionist Claude Monet which are on display at museums across the world |
| 20% | DATA | 4 | With 26-Down, information stored locally on a computer |
| 20% | MEMO | 4 | With 26 Down, box on an office desk |
| 20% | FEBRUARYTWELFTH | 15 | 1924 day on which 19 Across premiered |
| 20% | ATLANTABRAVES | 13 | Team with which 18-Across won the 1995 World Series: 2 wds. |
| 20% | FASHIONPOLICE | 13 | E! reality series on which judges discuss celebrities' clothing choices: 2 wds. |
| 20% | ELEMENTARY | 10 | 2012-2019 mystery series on which Lucy Liu played Dr. Joan Watson |
| 20% | THEFIRSTLADY | 12 | Showtime anthology series on which Gillian Anderson played Eleanor Roosevelt: 3 wds. |
| 19% | POLKA | 5 | With 11 Across, design on some dresses |