| 46% | SARAH | 5 | With 35-Across, "The Glass Castle" actress who plays Logan Roy's daughter Siobhan on "Succession" |
| 44% | WARREN | 6 | With 35-Across, actor who played Clyde, one of the title characters on the run in 1967's "Bonnie and Clyde" |
| 43% | MELISSA | 7 | With 33-Across, actress who plays Kara Danvers/Supergirl on The CW's "Supergirl" |
| 42% | KALEYCUOCO | 10 | "The Flight Attendant" actress who voices the title character on HBO Max's animated "Harley Quinn": 2 wds. |
| 41% | CONSTANCEWU | 11 | Actress who plays 36-Across's mother on "Fresh off the Boat" (2 wds.) |
| 41% | CAMILLERAZAT | 12 | Actress who plays the title character's new friend on 46-Across (2 wds.) |
| 41% | PARE | 4 | Jessica ___, actress who plays Megan Draper on the TV series "Mad Men" |
| 40% | FELICITY | 8 | With 55-Across, English actress who plays the first wife of 35-Across in "The Theory of Everything" |
| 40% | BARBARABARRIE | 13 | "Breaking Away" actress who played the title character's Nana on 46-Across (2 wds.) |
| 40% | KATEY | 5 | With 35-Across, "Sons of Anarchy" actress who plays the title character in "Rebel" |
| 40% | JAYNEATKINSON | 13 | "House of Cards" actress who plays the U.S. Attorney General on 34-Across (2 wds.) |
| 39% | SYDNEYSWEENEY | 13 | "White Lotus" actress who plays Cassie Howard on HBO's "Euphoria" (2 wds.) |
| 39% | GINARODRIGUEZ | 13 | Actress who plays the title role on 15-Across: 2 wds. |
| 39% | LILYCOLLINS | 11 | Actress who plays the title character on 46-Across (2 wds.) |
| 39% | LILIREINHART | 12 | Actress who plays Betty on the CW's "Riverdale": 2 wds. |
| 38% | EMILYMORTIMER | 13 | Actress who plays MacKenzie McHale, the executive producer on 37-Across: 2 wds. |
| 38% | JACLYNSMITH | 11 | Actress who played Kelly Garrett on the original "Charlie's Angels" (2 wds.) |
| 38% | FARRAHFAWCETT | 13 | Actress who played Jill Munroe on the original "Charlie's Angels" (2 wds.) |
| 38% | KATEJACKSON | 11 | Actress who played Sabrina Duncan on the original "Charlie's Angels" (2 wds.) |
| 38% | MARTIN | 6 | With 35-Across, actor who played Rollin Hand on "Mission: Impossible" |
| 38% | LUCYLIU | 7 | Actress who plays 22-Across/41-Across on the CBS series "Elementary" (2 wds.) |
| 38% | JESSSALGUEIRO | 13 | Actress who plays Freddy's roommate on the Paramount+ reboot of "Frasier" (2 wds.) |
| 38% | ISABELSANFORD | 13 | Actress who played Louise on "All in the Family" and 45-Across (2 wds.) |
| 38% | MEGAN | 5 | With 53-Across, actress who played Elizabeth Keen on "The Blacklist" |
| 38% | KATHERINEHEIGL | 14 | "Grey's Anatomy" actress who plays Tully Hart on the Netflix adaptation of 41-Across (2 wds.) |
| 38% | LUCYLIU | 7 | Actress who played Joan (based on 47-Across) on the CBS series "Elementary": 2 wds. |
| 38% | CHERYLHINES | 11 | Actress who plays the main character's ex-wife on "Curb Your Enthusiasm": 2 wds. |
| 37% | ALYSSA | 6 | With 37-Across, "Charmed" actress who played Tony's daughter Samantha on 18-Across |
| 37% | LOUISAHARLAND | 13 | "Derry Girls" actress who plays the title character on 44-Across (2 wds.) |
| 37% | TALITHABATEMAN | 14 | "Annabelle: Creation" actress who plays the astronaut's daughter on "Away": 2 wds. |