| 100% | THEICE | 6 | With 37-Across, drama set in New York's Last Chance Saloon |
| 46% | LAW | 3 | "___ & Order" (crime drama set in New York City) |
| 46% | ORDER | 5 | "Law & ___" (crime drama set in New York City) |
| 41% | RENT | 4 | 1996 musical set in New York's Alphabet City |
| 41% | RENT | 4 | Rock musical set in New York's East Village |
| 39% | THEDOLLHOUSE | 12 | Novel by 39-Across set in New York City's Barbizon Hotel (2 wds.) |
| 38% | DIRTYDANCING | 12 | 1987 coming-of-age movie set in New York's Catskill Mountains: 2 wds. |
| 38% | THINMAN | 7 | Classic 1934 novel set in Prohibition-era New York City, with "The" |
| 38% | GEMS | 4 | "Uncut ___" (Adam Sandler film set in New York City's Diamond District) |
| 38% | THEADDRESS | 10 | Novel by 39-Across set in New York City's apartment building The Dakota (2 wds.) |
| 37% | MADABOUTYOU | 11 | 1990s sitcom set in New York |
| 37% | SEXANDTHECITY | 13 | HBO sitcom set in New York |
| 37% | EST | 3 | Clock setting in New York: Abbr. |
| 37% | LAW | 3 | "___ & Order" (TV show set in New York) |
| 36% | NCIS | 4 | Drama with spinoffs set in L.A. and New Orleans |
| 36% | WASHI | 5 | Henry James novel set in New York City |
| 36% | POSE | 4 | 2018-2021 FX series set in New York |
| 36% | EDT | 3 | Summer clock setting in New York City: Abbr. |
| 36% | TAXI | 4 | "___ Driver" (Robert DeNiro film set in New York City) |
| 36% | FRIENDS | 7 | 1994-2004 NBC sitcom set in New York City |
| 35% | WESTSIDESTORY | 13 | Natalie Wood film set in New York City (3 wds.) |
| 35% | WALLSTREET | 10 | Michael Douglas film set in New York City (2 wds.) |
| 35% | TAXI | 4 | "___ Driver" (Robert De Niro film set in New York City) |
| 35% | HARLEMSHUFFLE | 13 | Colson Whitehead novel set in New York City (2 wds.) |
| 35% | THEGILDEDAGE | 12 | HBO historical drama created by 32-Across set in New York City in the 1880s (3 wds.) |
| 35% | TAXIDRIVER | 10 | Robert De Niro film set in New York City (2 wds.) |
| 35% | HARLEMSHUFFLE | 13 | 2021 Colson Whitehead novel set in New York City (2 wds.) |
| 35% | MADABOUTYOU | 11 | Sitcom set in New York City that featured Carol Burnett in a recurring role as Jamie's mother (3 wds.) |
| 35% | MANHATTAN | 9 | Borough in New York with Wall Street |
| 35% | SALMA | 5 | With 37-Across, "Eternals" actress who plays Kitty Softpaws in "Puss in Boots: The Last Wish" |