| 100% | DISCO | 5 | With 4-Down, "The Simpsons" character in a rhinestone-studded leisure suit |
| 74% | STU | 3 | Disco ___ ("The Simpsons" character in a rhinestone-studded leisure suit) |
| 72% | DISCO | 5 | With 8-Down, "The Simpsons" character in a rhinestone suit |
| 56% | STU | 3 | Disco ___ ("The Simpsons" character in a leisure suit) |
| 46% | HOMER | 5 | The Simpsons character who bets against Lisa in a crossword tournament |
| 45% | MILEY | 5 | With 4-Down, “Party in the U.S.A.” singer |
| 44% | NANCY | 5 | ___ Downs, character with a goth aesthetic played by Fairuza Balk in "The Craft" |
| 43% | APU | 3 | "The Simpsons" character in a green jacket |
| 43% | NED | 3 | "The Simpsons" character in a green sweater |
| 42% | RAHEEM | 6 | Character with a boombox in "Do the Right Thing" |
| 42% | CRIED | 5 | With 4-Down, threw in the towel |
| 42% | AYE | 3 | With 4-Across, what the pirate said on his 80th birthday, in a dad joke |
| 41% | PEARL | 5 | With 4 Down, site of the attack that on today's date in 1941 lead to the US entering WWII |
| 41% | THE | 3 | With 4-Down, last two words in a story |
| 41% | PLUMB | 5 | With 111 Down, crazy as a loon, in the Crazy A Saloon |
| 41% | BATMAN | 6 | Wearer of a suit with nipples in the nineteen-nineties |
| 41% | OTTO | 4 | "The Simpsons" character with a palindromic name |
| 41% | APU | 3 | "The Simpsons" character with a Ph.D. |
| 40% | DOROTHY | 7 | Character who sings with the Scarecrow in "If I Only Had a Brain" |
| 40% | LOUIS | 5 | With 4-Down, monarch with the longest verifiable reign in history |
| 40% | ROSALINA | 8 | Magical character in the Super Mario games who wears a turquoise dress with a silver crown |
| 40% | THEFONZ | 7 | Sitcom character with a leather jacket that's now in the Smithsonian |
| 40% | BIBLE | 5 | With 4-Down, much of the Southeast U.S. is in it |
| 40% | TOADETTE | 8 | Childlike character in the Super Mario games who wears a pink dress with a pink mushroom hat |
| 40% | AMORE | 5 | It makes you "dance down the street with a cloud at your feet," in a 1953 hit |
| 39% | BRAKE | 5 | With 4-Down, what may be cut to sabotage a car in movies |
| 39% | OTTER | 5 | “The Wind in the Willows” character with a “broad glistening muzzle” |
| 39% | OTTO | 4 | "The Simpsons" character with a habit of calling things "gnarly" |
| 39% | APU | 3 | "The Simpsons" character with a Ph.D. from Calcutta Tech |
| 39% | APU | 3 | "The Simpsons" character who has a PhD in computer science |