| 100% | MEGANTHEE | 9 | With 46-Across, rapper who collaborated with Beyoncé on the 2020 #1 hit "Savage (Remix)": 2 wds. |
| 74% | SEANPAUL | 8 | Rapper who collaborated with Beyoncé on the 2003 #1 hit "Baby Boy": 2 wds. |
| 65% | EDSHEERAN | 9 | Singer who collaborated with Beyoncé on the 2017 #1 hit "Perfect Duet": 2 wds. |
| 55% | KATYPERRY | 9 | Singer who collaborated with Snoop Dogg on the 2010 No. 1 Billboard hit "California Gurls" (2 wds.) |
| 52% | CAMILACABELLO | 13 | Singer who collaborated with Machine Gun Kelly in 2017 on the #4 hit "Bad Things": 2 wds. |
| 51% | KENDRICKLAMAR | 13 | Rapper who duetted with SZA on 2024's "Luther," a #1 hit for 13 weeks: 2 wds. |
| 51% | JIMMIEALLEN | 11 | "Best Shot" singer who collaborated with Brad Paisley on the 2021 country hit "Freedom Was a Highway": 2 wds. |
| 50% | MEGANTHEE | 9 | With 46-Across, "Savage" rapper who both hosted and was the musical act in a 2022 "SNL" episode: 2 wds. |
| 50% | ALISONKRAUSS | 12 | "When You Say Nothing At All" singer who collaborated with Brad Paisley on the 2004 country hit "Whiskey Lullaby": 2 wds. |
| 50% | DOLLYPARTON | 11 | "Jolene" singer who collaborated with Brad Paisley on the 2005 country hit "When I Get Where I'm Going": 2 wds. |
| 49% | REGINABELLE | 11 | "Baby Come to Me" singer who collaborated with 44-Across on the R&B hits "Without You" and 34-Across (2 wds.) |
| 49% | THOMASRHETT | 11 | Singer/songwriter who collaborated with 17-Across, 28-Across, Reba McEntire, and Keith Urban on the country hit "Be a Light" (2 wds.) |
| 47% | DRAKE | 5 | One-named rapper who collaborated with 21 Savage on the 2022 album "Her Loss" |
| 47% | SWAE | 4 | Rapper ___ Lee, who collaborated with Post Malone on the hit song "Sunflower" |
| 47% | MEGANTHEE | 9 | With 43-Across, "Savage" rapper who was named a Revlon Global Brand Ambassador in 2020: 2 wds. |
| 46% | DADDYYANKEE | 11 | Rapper/singer who duetted with Luis Fonsi on 2017's "Despacito," a #1 hit for 16 weeks: 2 wds. |
| 46% | TOBYKEITH | 9 | Singer who duetted with Willie Nelson on the 2003 #1 country hit "Beer for My Horses": 2 wds. |
| 46% | NOELGALLAGHER | 13 | Guitarist who played with his brother Liam on the Oasis hit "Wonderwall": 2 wds. |
| 46% | ARIANAGRANDE | 12 | "7 Rings" pop singer who partnered with Justin Bieber on the 2020 #1 song "Stuck With U": 2 wds. |
| 45% | YOUNGTHUG | 9 | "Bad Boy" rapper who cowrote the top 10 hit "Go Crazy" with Chris Brown: 2 wds. |
| 45% | ALLIWANTFOR | 11 | With 33-Across, holiday tune that hit #1 on the Billboard charts in 2019, 2020, and 2021: 4 wds. |
| 44% | SAYSO | 5 | 2020 song by 14-Across that later hit #1 when remixed with Nicki Minaj: 2 wds. |
| 44% | TYDOLLASIGN | 11 | "Ain't Nothing" rapper who collaborates with 49-Across on 31-Across (3 wds.) |
| 44% | KENDRICKLAMAR | 13 | "To Pimp a Butterfly" rapper, who collaborated with Taylor Swift on "Bad Blood", a song from her fifth album: 2 wds. |
| 44% | SHERYLCROW | 10 | "All I Wanna Do" singer who collaborated with Kid Rock on his biggest pop hit, "Picture," in 2002: 2 wds. |
| 43% | IGGYAZALEA | 10 | "Fancy" singer featured on "Problem" who in 2014 became the second ever to be simultaneously #1 and #2 with her first two hits: 2 wds. |
| 43% | THEKIDLAROI | 11 | "Without You" rapper who partnered with Justin Bieber on the 2021 #1 song "Stay": 3 wds. |
| 43% | EMMYLOUHARRIS | 13 | Country Music Hall of Fame singer who collaborated with 28-Across and 43-Across on the Grammy-winning 1987 album "Trio" (2 wds.) |
| 42% | KANYEWEST | 9 | Rapper who performed "Jesus Walks" on the SNL40 anniversary special: 2 wds. |
| 42% | ARIANAGRANDE | 12 | "Thank U, Next" pop singer who got her seventh #1 hit with a remix of 38-Across: 2 wds. |