| 100% | DAVID | 5 | With 47-Across, "Doctor Who" actor who plays the demon Crowley on 30-Across |
| 62% | MICHAEL | 7 | With 17-Across, "Masters of Sex" actor who plays the angel Aziraphale on 30-Across |
| 58% | ROBERTSEAN | 10 | With 25-Across, actor who played Dr. James Wilson (based on 47-Across) on the Fox series "House": 2 wds. |
| 54% | CHRIS | 5 | With 30-Across, "Guardians of the Galaxy" actor who plays Owen Grady in 15-Across/47-Across |
| 53% | PAUL | 4 | With 50-Across, "Ant-Man" actor who plays a murdered Hollywood actor on "Only Murders in the Building" |
| 52% | HURT | 4 | Actor John who played the War Doctor on "Doctor Who" |
| 52% | PETERCAPALDI | 12 | "In the Loop" actor who played the Twelfth Doctor on "Doctor Who" (2 wds.) |
| 51% | BUDDY | 5 | With 33-Across, actor who played Jed on "The Beverly Hillbillies" |
| 50% | JOHNNYDEPP | 10 | "Murder on the Orient Express" actor who plays retired detective Russell Poole in 47-Across (2 wds.) |
| 50% | DAVID | 5 | With 29-Across, "Carnival Row" actor who plays Foreign Secretary Austin Dennison on "The Diplomat" |
| 50% | CRAIGTNELSON | 12 | "Parenthood" actor who plays the title role on 60-Across (3 wds.) |
| 50% | WARREN | 6 | With 35-Across, actor who played Clyde, one of the title characters on the run in 1967's "Bonnie and Clyde" |
| 50% | DAVID | 5 | Scottish actor Tennant who played the Doctor on "Doctor Who" |
| 49% | MICHAELK | 8 | With 34-Across, "The Wire" actor who plays Bobby McCray on "When They See Us": 2 wds. |
| 49% | NOAH | 4 | Actor Wyle who plays an ER doctor on the Max show "The Pitt" |
| 49% | PATRICKSTEWART | 14 | "X-Men" actor who plays the title role on 50-Across (2 wds.) |
| 49% | BOBODENKIRK | 11 | "Breaking Bad" actor who plays the lead role on 33-Across: 2 wds. |
| 49% | DONJOHNSON | 10 | "Miami Vice" actor who played the title character on 40-Across (2 wds.) |
| 49% | JASON | 5 | With 36-Across, Honolulu-born actor who played the title role in "Aquaman" |
| 49% | ASHER | 5 | With 34-Across, "Andi Mack" actor who plays the younger version of 38-Across in "Shazam!" |
| 49% | RAMONRODRIGUEZ | 14 | "Charlie's Angels" actor who plays the title role on 16-Across: 2 wds. |
| 49% | SPENCERTRACY | 12 | Actor who played the lawyer based on Clarence Darrow in 32-Across: 2 wds. |
| 49% | GABRIELBASSO | 12 | "The Whole Truth" actor who plays Peter Sutherland on 30-Across (2 wds.) |
| 48% | CHRIS | 5 | With 32-Across, "The Lego Movie" actor who played Andy Dwyer on "Parks and Recreation" |
| 48% | TIMOTHEE | 8 | With 35-Across, "Little Women" actor who plays the lead character Paul Atreides in "Dune" |
| 48% | FREDRICMARCH | 12 | Actor who played the lawyer based on William Jennings Bryan in 32-Across: 2 wds. |
| 48% | CHAR | 4 | Actor who played a character with the same first name on "Two and a Half Men" |
| 48% | SEANGIAMBRONE | 13 | Actor who plays the geeky boy, Adam, on 18-Across: 2 wds. |
| 47% | ELBA | 4 | Actor who played the title role on “Luther” |
| 47% | STACY | 5 | With 30-Across, "The Bourne Legacy" actor who plays John Gotti's mentor in "Gotti" |