| 100% | AMINO | 5 | With 94-Across, protein part |
| 61% | DISC | 4 | With 65 Across, Xbox part |
| 57% | WHATSYOUR | 9 | With 94 Across, a fashion question that Peter Pan is really tired of hearing? |
| 50% | AMINO | 5 | With 22-Across, protein building block |
| 48% | EDWARDWITHTOMSSUPPORT | 21 | With 94- and 106-Across, the end of the story |
| 47% | OUTER | 5 | With 29-Across, an anatomical part |
| 47% | YOUGOYOURWAY | 12 | With 49-Across, comment upon parting |
| 46% | PALO | 4 | With 4-Across, part of Silicon Valley |
| 46% | INK | 3 | With 43-Across, part of a squid |
| 46% | AMINO | 5 | With 16-Across, component of most proteins |
| 46% | LAD | 3 | 94 Across fellow |
| 46% | NOAH | 4 | 94 Across builder |
| 46% | RACED | 5 | 94 Across competitively |
| 45% | OOLO | 4 | With 121-Across, part of an afternoon repast |
| 45% | AREA | 4 | With 8-Across, part of a phone number |
| 45% | ERYKAH | 6 | With 47-Across, "New Amerykah Part One" musician |
| 45% | EYE | 3 | Body part with a 63-Across |
| 44% | SECOND | 6 | With 118-Across, part of a child's schooling |
| 44% | CENTRAL | 7 | With 68-Across, the circled part of this crossword |
| 44% | RORSCHACH | 9 | With 42-Across, part of a psychologist's battery |
| 44% | UVEAS | 5 | Eye parts with 38-Acrosses |
| 44% | KILO | 4 | With 94 Down, metric measures |
| 43% | AMANEVERYTIME | 13 | (See 94 Across) |
| 43% | FUNNY | 5 | With 8-Across, "humorous" part of the body near the humerus |
| 43% | FLIP | 4 | With 65-Across, part of a record ... or what each of this puzzle's five long Across answers has? |
| 43% | KNICKKNACK | 10 | With 44-Across, part of a children's song refrain |
| 42% | AERO | 4 | Prefix with 94-Down |
| 42% | CEDE | 4 | Part with |
| 42% | SUDOKU | 6 | With 67-Across, what the circled part of this crossword represents |
| 42% | FIRST | 5 | With 9-Across, part one of the Moderna and Pfizer vaccines |