| 100% | DOLLY | 5 | World's first cloned sheep |
| 63% | SNUPPY | 6 | Afghan hound, the world's first cloned dog |
| 61% | DOLLY | 5 | Name of the first cloned sheep |
| 54% | DOLLY | 5 | First successfully cloned sheep |
| 50% | STONE | 5 | World's first national park |
| 49% | DALLASACES | 10 | World's first professional bridge team |
| 48% | CHATTANOOGACHOOCHOO | 19 | World's first certified gold record, 1942 |
| 48% | MACGILL | 7 | World's first female airplane designer, Elsie __ |
| 48% | ENIAC | 5 | World's first general purpose electronic computer |
| 48% | DOLLY | 5 | Domestic sheep who was the first mammal to be cloned |
| 47% | SAS | 3 | World's first carrier with a transpolar route |
| 47% | DOLLY | 5 | Sheep who was the first cloned mammal |
| 46% | MIR | 3 | World's first continuously inhabited long-term space station |
| 46% | SPUTNIK | 7 | The world's first constructed satellite |
| 45% | HBO | 3 | World's first TV channel to be transmitted via satellite |
| 45% | HAITI | 5 | The world's first Black-led republic |
| 45% | DOLLY | 5 | Cloned sheep |
| 44% | CHURCH | 6 | Ellen, world's first female flight attendant |
| 44% | EWE | 3 | First cloned mammal |
| 44% | SHEEP | 5 | First cloned mammal |
| 43% | LONDON | 6 | Site of the world's first subway |
| 43% | NAPLES | 6 | Site of the world's first pizzeria |
| 42% | NIHAO | 5 | "Hello," in the world's most common first language |
| 42% | HATH | 4 | Verb in the world's first telegraph message |
| 42% | SEIKO | 5 | Maker of the world's first quartz watch |
| 42% | VIZCAYA | 7 | __ Bridge, world's first transporter bridge, Spain |
| 42% | DOLLY | 5 | Famous cloned sheep |
| 41% | NEWHAVEN | 8 | City with the world's first telephone directory (1878) |
| 41% | TELETHON | 8 | Milton Berle hosted the world's first one |
| 41% | SMALLPOX | 8 | Disease eradicated by the world's first vaccine |