| 100% | MDII | 4 | Year Columbus' fourth and last voyage began |
| 64% | MDII | 4 | Year Columbus began his last voyage |
| 45% | MDII | 4 | Year of Columbus's last voyage |
| 38% | AGELONG | 7 | Lasting for years and years |
| 37% | ISABELLA | 8 | Columbus voyage funders; monarchs Ferdinand and __ |
| 37% | MDIV | 4 | Year Columbus returned from his final voyage to the New World |
| 37% | DISCO | 5 | Grammy category whose first and last year was 1979 |
| 35% | MDIV | 4 | XII years after Columbus's first voyage |
| 34% | DRAGON | 6 | Year of the ___ (Chinese zodiac observance that began last month) |
| 33% | PSALM | 5 | Kanye and Kim's youngest, born in May, last year |
| 32% | CNN | 3 | Rival that ranked behind both Fox News and MSNBC last year |
| 32% | SAN | 3 | Beginning of the names of California’s second, third, and fourth most populous cities |
| 32% | ALLPRO | 6 | AP gridiron selection that last year included Lamar Jackson and Justin Tucker |
| 31% | MEATTORNADO | 11 | Fictional burrito on "Parks and Recreation" that "literally killed a guy last year" |
| 31% | BON | 3 | Voyage beginning? |
| 31% | INCHES | 6 | Fourth and ___ |
| 30% | MDVI | 4 | Year Columbus died |
| 30% | TOLEDO | 6 | Fourth-largest city of Ohio after Columbus, Cleveland, and Cincinnati |
| 29% | EVO | 3 | President Morales of Bolivia who resigned last year and received political asylum from Mexico and Argentina |
| 29% | ROBS | 4 | Lowe of Fox's "Mental Samurai" and Zombie who directed last year's "3 from Hell" |
| 29% | HALLEY | 6 | Comet that is visible from Earth every 75-76 years and was last seen in 1986 |
| 29% | INCHES | 6 | Fourth and ___ (exciting football situation) |
| 28% | EVER | 4 | Green and lasting |
| 28% | PENTHOUSES | 10 | What Julia Roberts and Britney Spears listed last year for over $5 million and $7 million respectively |
| 28% | CRAM | 4 | Study hard and late |
| 27% | HARPERLEE | 9 | Author of the book that Times readers voted the best of the last hundred and twenty-five years |
| 27% | ANNABELLEE | 10 | Classic poem that begins "It was many and many a year ago / In a kingdom by the sea" |
| 27% | NOW | 3 | ___ and Later (candy similar to Starburst) |
| 27% | EVER | 4 | It precedes more and lasting |
| 27% | TOO | 3 | Word before little and late |