| 100% | MMI | 3 | Year in a Roman sci-fi film? |
| 61% | MOON | 4 | "Destination" in a 1950 sci-fi film |
| 58% | KPAX | 4 | Title planet in a 2001 sci-fi film |
| 56% | TRON | 4 | Classic sci-fi film with a sequel 28 years later |
| 56% | ALIEN | 5 | Figure in many a sci-fi film |
| 55% | APE | 3 | Dr. Cornelius, in a sci-fi film series |
| 55% | NEO | 3 | "The One," in a sci-fi film series |
| 55% | SOYLENTGREEN | 12 | 1973 sci-fi film starring Charlton Heston set in the year 2022 |
| 55% | UFO | 3 | Space vehicle in a sci-fi film, perhaps: Abbr. |
| 55% | UFO | 3 | Alien spacecraft in a sci-fi film, say: Abbr. |
| 55% | HANSOLO | 7 | Killer of Greedo in a sci-fi film |
| 55% | APES | 4 | Heston's jailors, in a sci-fi film |
| 54% | LII | 3 | Approximate number of weeks in a Roman year |
| 53% | DARYL | 5 | 1985 sci-fi film featuring Barret Oliver in the title role as a cyborg |
| 53% | ROLLERBALL | 10 | Titular sport in a 1975 dystopian sci-fi film |
| 53% | MARS | 4 | Planet in a 2015 Matt Damon sci-fi film |
| 53% | TRON | 4 | 1982 sci-fi film set in a computer |
| 53% | CGI | 3 | Tool used in many a sci-fi film |
| 53% | HOLOGRAM | 8 | 3D image in many a sci-fi film |
| 53% | WATER | 5 | "Avatar: The Way of ___," 2022 sci-fi film that was in production for 12 years |
| 51% | THEMARTIAN | 10 | 2015 sci-fi film in which Jessica Chastain played a mission commander rescuing an astronaut: 2 wds. |
| 51% | INCEPTION | 9 | A 2010 Sci-Fi film by Christopher Nolan in which Tom Hardy plays a fence who can impersonate others expertly |
| 50% | ASPACEODYSSEY | 13 | Subtitle of a classic sci-fi film that premiered in April 1968 (3 wds.) |
| 50% | THEFORCE | 8 | Source of power in a series of blockbuster sci-fi films |
| 50% | COVENANT | 8 | Sci-fi horror film directed by Ridley Scott, "Alien: ___," which is a sequel to "Prometheus," and released in 2017 |
| 50% | THING | 5 | "The ___," 1982 sci-fi horror film starring Kurt Russell that got a nostalgic nod in "Stranger Things" |
| 49% | THEMATRIX | 9 | A 1999 Sci-Fi film in which Keanu Reeves - whose birthday it is today - portrays the main character, named "Neo": 2 wds. |
| 48% | TOEARTH | 7 | How David Bowie's character fell, in a 1976 sci-fi film |
| 48% | AREA | 4 | "___ 51," 2015 sci-fi horror film with the number of a famous, highly classified Air Force facility in its title |
| 47% | HAMM | 4 | Actor Jon who plays a hologram in the sci-fi film "Marjorie Prime" |