| 100% | THEE | 4 | You, once |
| 100% | THOU | 4 | You, once |
| 91% | IVE | 3 | "If ___ told you once ..." |
| 91% | IVE | 3 | ''If __ told you once . . .'' |
| 89% | ALMA | 4 | ___ mater (school you once attended) |
| 87% | ALMA | 4 | ___ mater (school you once went to) |
| 87% | CHILD | 5 | Me and you, once |
| 87% | YOLO | 4 | You only live once |
| 83% | TWITTER | 7 | The website where you once left your tweets |
| 78% | RUSSIANROULETTE | 15 | Game you can lose only once |
| 76% | SLICKER | 7 | Kitchen gadget you've used maybe once |
| 76% | DIALO | 5 | How you could get a number, once |
| 76% | ECHO | 4 | Sound that you hear more than once |
| 76% | FOOLME | 6 | __ once, shame on you; Italian proverb |
| 75% | FOOL | 4 | "___ me once, shame on you ..." |
| 75% | FOOL | 4 | "___ me once, shame on you..." |
| 75% | SHAME | 5 | "Fool me once, ___ on you..." |
| 74% | OILOFOLAY | 9 | "Love the skin you're in" sloganeer, once |
| 74% | PRINGLES | 8 | Once you pop the fun don't stop |
| 74% | LIRE | 4 | Where you could once see Montessori and Marconi |
| 72% | MITCHUM | 7 | "So effective you can skip a day" sloganeer, once |
| 70% | PRINGLES | 8 | Once you pop, you can't stop eating these chips |
| 70% | TABS | 4 | They let you stay on multiple web pages at once |
| 70% | AUCTION | 7 | Event where you may hear, "Going once... going twice... sold!" |
| 69% | ROOTS | 5 | You might put these down once you've found a place to stay |
| 68% | EXILE | 5 | Once you're forced into this, there's no going back |
| 68% | RENTTOOWN | 9 | Like furniture you don't pay for all at once: Hyph. |
| 67% | DELTA | 5 | Airline once said to be "ready when you are" |
| 67% | AMEN | 4 | Word said once you are done with 8-Across |
| 67% | JAMS | 4 | They're like pickles, once you're in them |