| 100% | PILLOWTALK | 10 | Zayn Malik's first solo #1 hit, in 2016 |
| 43% | BEN | 3 | Michael Jackson's first #1 solo hit |
| 42% | THIRTEEN | 8 | Age of Michael Jackson at first solo number 1 hit |
| 39% | OSLIN | 5 | K.T. with four No. 1 hits in the U.S. |
| 37% | RITA | 4 | Singer Ora with three solo #1 hits in Britain |
| 37% | BETTER | 6 | 2018 song that was 17-Across's first solo top 10 hit |
| 37% | JACKIESTILES | 12 | 2016 Women's Basketball Hall of Fame inductee who was the first Division I player to score over 1,000 points in a season: 2 wds. |
| 36% | ALBERTPUJOLS | 12 | First baseman with over 1,000 hits for one team in each league (Cardinals and Angels): 2 wds. |
| 35% | LADY | 4 | "___ Marmalade" (No. 1 hit in 1974 and 2001) |
| 33% | HAN | 3 | First name in Solo flying? |
| 33% | AMELIA | 6 | First name in solo flying |
| 33% | SOS | 3 | Rihanna's first #1 hit |
| 33% | EYEOFTHETIGER | 13 | Survivor song that was a No. 1 hit in 1982 (4 wds.) |
| 33% | GENIE | 5 | "___ in a Bottle" (Christina Aguilera's first No. 1 song) |
| 33% | GENIE | 5 | "___ in a Bottle" (Christina Aguilera's first big hit) |
| 33% | TEENANGEL | 9 | 1960 No. 1 hit heard in "American Graffiti" |
| 33% | HAN | 3 | First name of Solo, in "Solo" |
| 33% | SERVE | 5 | First hit in a tennis match |
| 33% | BEN | 3 | Michael Jackson's first #1 hit |
| 33% | YOUSENDME | 9 | Sam Cooke's first #1 hit |
| 33% | LOW | 3 | Flo Rida's first #1 hit |
| 33% | BERNIE | 6 | First name in the 2016 campaign |
| 32% | OBOE | 4 | It has a brief solo in the first movement of Beethoven's Fifth |
| 32% | ONEDANCE | 8 | Single off of 34-Across that hit #1 in May 2016: 2 wds. |
| 32% | THEE | 4 | Megan ___ Stallion, rapper with two Billboard No. 1 hits in 2020 (“Savage,” “WAP”) |
| 32% | PILLOWTALK | 10 | 2016 Zayn hit whose title suggests bedtime |
| 32% | OUR | 3 | "___ Song" (Taylor Swift's first #1 hit) |
| 32% | ANNEMURRAY | 10 | First Canadian female solo artist to reach No. 1 on the U.S. Billboard Hot 100 |
| 32% | ROSA | 4 | First name in December 1, 1955 headlines |
| 32% | STRATEGIC | 9 | First S in OSS, precursor of CIA |